Evidence map›Paper›PMID 41664107›Full record

ArticleBMC musculoskeletal disorders2026

Comparison of the clinical outcomes between the modified free musculocutaneous flap combined with delayed bone reconstruction technique and the free fasciocutaneous flap combined with Masquelet technique for post-traumatic osteomyelitis of the lower leg.

Liang Hu, Nan Liu, Neng Jin, Changming Guo, Feixiang Chen, Shuming Ye

Abstract readComparative Study
In one paragraph

Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Liang HuDepartment of Orthopedic, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230000, China.
Nan LiuThe Second Affiliated Hospital of Bengbu Medical College, Bengbu, 233000, China.
Neng JinDepartment of Orthopedic, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230000, China.
Changming GuoDepartment of Orthopedic, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230000, China.
Feixiang ChenDepartment of Orthopedic, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230000, China.
Shuming YeDepartment of Orthopedic, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230000, China. yeshumingsuda@163.com.

Funding

Anhui Province Open Research Project Fund AHTT2024B003Anhui Provincial Institute of Translational Medicine Research Project Fund 2022zhyx-C55Natural Science Youth Project of Bengbu Medical College 2024byzd097Scientific Research Innovation Project Fund of Bengbu City 2024ZD0031
6 · The paper itself

Abstract

objectivePost-traumatic osteomyelitis of the lower leg commonly involves severe infectious bone and soft tissue defects, posing significant reconstructive challenges and a high risk of infection recurrence. While both the free fasciocutaneous flap with Masquelet technique (FFCMT) and the modified free musculocutaneous flap with delayed bone reconstruction (MMDRT) have been described, their comparative efficacy remains unelucidated. This study aimed to evaluate and compare the clinical outcomes of FFCMT and MMDRT in managing such complex defects.

methodsThis retrospective cohort study included 45 patients with post-traumatic osteomyelitis of the lower leg who received MMDRT (22 cases) and FFCMT (23 cases) treatments at our hospital from January 2016 to August 2023. The demographic data, underlying diseases, ASA, bone and soft tissue defects, surgical data, and postoperative follow-up results of the two groups were documented for analysis. By comparing the bone union time, infection control efficiency, and postoperative complications of the patients in the two groups, the efficacy differences of the two surgical methods were systematically evaluated.

resultsThe MMDRT group showed significant superiority over the FFCMT group in terms of bone union time (MMDRT:13.06 ± 1.14 months; FFCMT: 14.35 ± 1.01 months), the time for white blood cell and C-reactive protein indicators to return to normal, and the incidence of fracture-related complications (P < 0.05). However, there were no significant differences between the two groups in terms of the number of debridement procedures, operation time, blood loss, flap complications, and the final follow-up tibial healing RUST score and ankle AOFAS score (P > 0.05).

conclusionThe successful management of post-traumatic osteomyelitis hinges on effective infection control, coverage with well-vascularized tissue, and reconstruction of bone defects. While both MMDRT and FFCMT are effective for tibial osteomyelitis, MMDRT simplifies the bone grafting process, facilitating earlier infection control and shortening the fracture healing time.

Indexed as

Bone TransplantationFree Tissue FlapsLeg InjuriesMyocutaneous FlapOsteomyelitisPlastic Surgery ProceduresAdultFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung AdultDelayed bone reconstruction techniqueEfficacy comparisonFlap thinning techniqueFree fasciocutaneous flapFree musculocutaneous flapMasquelet techniqueNPWTPost-traumatic osteomyelitis of the lower leg

Identifiers

PMID41664107
PMCPMC13015172

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