Evidence map›Paper›PMID 41664092›Full record

SynthesisReproductive health2026

Primary and secondary infertility in India: a systematic review and meta-analysis.

Kshetrimayum Surmala Devi, Devika Mehra, Deepika Bahl, Mohammad Hamza, Leena Uppal, Sancheeta Ghosh, Subha Sankar Das, Sunil Mehra

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kshetrimayum Surmala DeviMAMTA Health Institute for Mother and Child, New Delhi, India.
Devika Mehra *MAMTA Health Institute for Mother and Child, New Delhi, India.
Deepika Bahl *MAMTA Health Institute for Mother and Child, New Delhi, India.
Mohammad HamzaMAMTA Health Institute for Mother and Child, New Delhi, India.
Leena UppalMAMTA Health Institute for Mother and Child, New Delhi, India.
Sancheeta GhoshMAMTA Health Institute for Mother and Child, New Delhi, India.
Subha Sankar DasMAMTA Health Institute for Mother and Child, New Delhi, India. das@mamtahimc.in.
Sunil MehraMAMTA Health Institute for Mother and Child, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfertility emerges as a notable health concern worldwide, affecting approximately 17.5% of couples. There is a lack of comprehensive estimates regarding its prevalence. This meta-analysis aims to address this gap by examining the combined prevalence of infertility, both primary and secondary in India.

methodsStudies conducted in India (1997–2023) reporting overall, primary and secondary infertility prevalence, among females aged 15–49 years were included through a systematic search in PubMed, ScienceDirect, and Google Scholar databases. Newcastle Ottawa scale was used to assess the quality of included studies. The meta-analysis employed a random-effects model and presented the combined prevalence along with 95% confidence interval (CI). Heterogeneity was evaluated using the I2 index, which allowed assessment of variability in the results across the different included studies.

resultsOut of 3,216 total studies, 10 were eligible for inclusion, and eight among those were included in the meta-analysis. Two studies were excluded based on quality assessment scores falling below the threshold of 50%. The eight studies represented 25,778 women of reproductive age, across various states in India. Most studies were conducted in community setup. The pooled prevalence of overall infertility, primary infertility and secondary infertility was 8% (95% CI: 0.01–0.14), 5% (95% CI: 0.03–0.06) and 2% (95% CI: 0.01–0.04) respectively.

conclusionInfertility urgently requires a comprehensive policy emphasising a strategic plan of action that addresses the public health concerns. Facilities that are accessible with equitable reproductive health care services within the overall RMNCH + A framework are needed for early identification and management of infertility.

Indexed as

Infertility, FemaleAdolescentAdultFemaleHumansIndiaPrevalenceFemaleIndiaInfertilityMeta- analysisPrevalence

Identifiers

PMID41664092
PMCPMC12983635

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.