ArticleBMC geriatrics2026
Viability of an educational program for lifestyle changes and an algorithm for the derivation of exercise programs in older people at risk of dependency at primary care: PRICA-POWFRAIL study protocol.
Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05772910 (Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.
Who cites it
1 citing paper in PubMed.
- Latent profile analysis and analytical model construction based on heterogeneity of intrinsic capacity in Chinese older adults.Frontiers in aging neuroscience · 2026Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundThis manuscript presents the study protocol of the PRICA-POWFRAIL randomized controlled trial. Frailty and pre-frailty are major predictors of functional decline and dependency in older adults, yet the implementation of personalized, scalable, and clinically interventions in primary care remains limited. This protocol describes the methodological design and planned evaluation of a lifestyle education programme and an individualized exercise-prescription algorithm aimed at improving intrinsic capacity and preventing dependency.
methodsThis is a multicentre, four-arm randomized controlled trial with a 10-week intervention period and a 12-month follow-up. A total of 110 adults aged ≥ 70 years identified as frail or pre-frail in primary care will be recruited and randomized (1:1:1:1) to one of four groups: (1) Education (EDU), (2) Exercise (EXER), (3) Combined Education-Exercise (EDU-EXER), or (4) Control. Primary outcomes include intrinsic capacity, physical function, and health-related quality of life. Secondary outcomes include digital mobility biomarkers, muscle and body composition measures, and blood-based biomarkers. A previous internal pilot study will inform final assumptions for sample size estimation. DISCUSSION: This protocol outlines a theoretically grounded and clinically implementable model combining lifestyle education and an individualized exercise algorithm adapted to the primary care context in south Spain. The findings will provide evidence regarding the potential clinical impact of the PRICA-POWFRAIL approach and will inform future strategies for early individualized intervention in frailty and pre-frailty.
trial registrationClinicalTrials.gov Identifier: NCT05772910.
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