Evidence map›Paper›PMID 41663967›Full record

ArticleBMC primary care2026

Long-term beta blocker prescribing after myocardial infarction in European primary care (PRACTITIONER).

Martina Zangger, Katharina Tabea Jungo, Limor Adler, Radost Assenova, Olivera Batic-Mujanovic, Luigi Bracchitta, Christine Brütting, Krzysztof Buczkowski, Jelena Danilenko, Patrick Erber and 17 more

Abstract read
In one paragraph

Article in BMC primary care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Martina ZanggerInstitute of Primary Health Care (BIHAM), University of Bern, Mittelstrasse 43, Bern, CH-3012, Switzerland.
Katharina Tabea JungoInstitute of Primary Health Care (BIHAM), University of Bern, Mittelstrasse 43, Bern, CH-3012, Switzerland.
Limor AdlerDepartment of Family Medicine, Gray's Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Radost AssenovaDepartment of Urology and General Practice, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria.
Olivera Batic-MujanovicDepartment of Family Medicine, Faculty of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina.
Luigi BracchittaPrimary Care Department, ATS Città Metropolitana di Milano, Milan, Italy.
Christine BrüttingInstitute of General Practice, Faculty of Medicine, University of Halle- Wittenberg, Halle (Saale), Saxony-Anhalt, Germany.
Krzysztof BuczkowskiDepartment of Family Medicine, Nicolaus Copernicus University in Torun, Torun, Poland.
Jelena DanilenkoDepartment of Family Medicine, Rīga Stradiņš University, MFD Health Group, Riga, Latvia.
Patrick ErberDivision General and Family Medicine, Department of General Health Studies, Karl Landsteiner University of Health Sciences, Krems, Austria.
Ileana Gefaell LarrondoPrimary Care Research Unit, Gerencia Asistencial de Atención Primaria, Madrid, Spain.
Oksana IlkovDepartment of Family Medicine and Outpatient Care, Medical Faculty, Uzhhorod National University, Uzhorod, Ukraine.
Katerina JavorskaDepartment of Preventive Medicine, Faculty of Medicine in Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Aisling A JenningsDepartment of General Practice, University College Cork, Cork, Ireland.
Tonje R JohannessenDepartment of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.
Tuomas KoskelaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Donata KurpasDivision of Research Methodology, Department of Nursing, Faculty of Nursing and Midwifery, Wroclaw Medical University, Wrocław, Poland.
Vanja LazićHealth Center Zagreb - Centar, Zagreb, Croatia.
Stina MannheimerInstitute of Health and Care Sciences, University of Gothenburg Centre for Person-Centred Care (GPCC), Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
Mahmoud MoussaDepartment of Primary Care Medicine, Medical University of Vienna, Vienna, Austria.
Martin SeifertDivision of General Practice, 3rd Faculty of Medicine, Charles University, Prague, Czechia, Czechia.
Deona TarajDepartment of Nursing, Faculty of Health, University of Vlora "Ismail Qemali," Vlora, Vlorë, Albania.
Peter TorzsaDepartment of Family Medicine, Semmelweis University, Budapest, Hungary.
Catarina Viegas DiasComprehensive Health Research Centre (CHRC), NOVA Medical School, NOVA University, Lisbon, Portugal.
Erika ZelkoInstitute for General Medicine, Johannes Kepler Universität Linz, Linz, Austria.
Baris GencerInstitute of Primary Health Care (BIHAM), University of Bern, Mittelstrasse 43, Bern, CH-3012, Switzerland.
Sven StreitInstitute of Primary Health Care (BIHAM), University of Bern, Mittelstrasse 43, Bern, CH-3012, Switzerland. sven.streit@biham.unibe.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe long-term use of beta blockers after myocardial infarction in patients with preserved ventricular function is debated. General practitioners (GPs) often decide whether to continue or discontinue long-term medications, yet little is known about how they apply evolving evidence to clinical prescribing decisions.

objectiveTo assess whether GPs are willing to deprescribe beta blockers post myocardial infarction with preserved left ventricular function and to identify factors associated with deprescribing decisions.

designCross-sectional online survey using case vignettes, conducted between July 2023 and October 2024 in primary care settings in 24 sites across 20 European countries.

participantsPracticing GPs recruited through convenience sampling at each site. MAIN MEASURES: The primary outcome was whether the GP chose to deprescribe beta blockers in the vignettes. Adjusted risk ratios for the association between GP characteristics and the decision to deprescribe were estimated using Poisson regression with generalized estimating equations and robust standard errors, accounting for clustering at the GP and country level. KEY

results604 GPs participated in the survey (median [IQR] age, 44.0 [35.0-54.8] years; 364 [60.3%] female), 89.2% deprescribed beta blockers in at least one vignette. The likelihood of deprescribing increased with time since myocardial infarction (adjusted risk ratio [RR] = 1.28; 95% CI 1.21–1.36 after 5 years; RR = 1.78; 95% CI 1.66–1.90 after 10 years vs. 3 months) and with side effects (RR = 1.76; 95% CI 1.66–1.88). More years of clinical experience were associated with a lower likelihood of deprescribing (RR = 0.86; 95% CI 0.77–0.95 for most vs. least experienced).

conclusionsIn this cross-national vignette study, most GPs were willing to deprescribe beta blockers after myocardial infarction in patients with preserved left ventricular function, particularly when time had passed and side effects were present. These findings suggest that GPs are open to applying evolving evidence on beta blocker discontinuation in clinical care.

Indexed as

Adrenergic beta-AntagonistsDeprescriptionsGeneral PractitionersMyocardial InfarctionPractice Patterns, Physicians'Cross-Sectional StudiesEuropeFemaleHumansMaleMiddle AgedPrimary Health CareAdrenergic beta-AntagonistsBeta blockerDeprescribingMyocardial infarctionPreserved left ventricular functionPrimary care

Identifiers

PMID41663967
PMCPMC12983531

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.