ArticleBMC geriatrics2026
Prevalence of symptoms and their association to health-related quality of life among older men in Sweden - a cross-sectional study.
Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSymptoms can negatively impact health-related quality of life (HrQoL) in older adults, yet data on their prevalence and impact in older men are limited. This study aimed to examine the prevalence of nine core symptoms and their associations with HrQoL in older men.
methodsA cross-sectional, population-based study was conducted among 907 men aged 73 years in Sweden. Participants rated nine symptoms on a 0-10 scale: pain, tiredness, sleepiness, nausea, loss of appetite, depression, anxiety, shortness of breath, and overall well-being. Symptoms were considered present if scored ≥ 1. HrQoL was measured using the physical and mental component scores of the Short-Form 12 Health Survey (SF-12v2). Associations were analyzed using linear regression adjusted for confounders.
resultsAmong participants, 16% reported respiratory diseases and 35% cardiovascular diseases. The most common symptoms were tiredness (78%), poor well-being (77%), and pain (73%). Depression and anxiety were reported by 46% and 32%, respectively. The strongest associations between symptoms and physical HrQoL were (beta coefficient; 95% confidence interval): pain (-2.05; -2.25 to -2.24), tiredness (-1.98; -2.22 to -1.74), and shortness of breath (-1.73; -1.97 to -1.49) and for mental HrQOL: depression (-3.50; -3.74 to -3.27), anxiety (-3.40; -3.70 to -3.11), drowsiness (-2.35; -2,64 to -2.07), and tiredness (-2.30; -2.56 to -2.03).
conclusionSymptoms are highly prevalent among older men and significantly associated with lower HrQoL and pain, tiredness, depression, and anxiety were the most impactful. These findings underscore the importance of targeted symptom screening and management to promote healthy aging and well-being.
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