Evidence map›Paper›PMID 41663845›Full record

ArticleSports medicine - open2026

Time to Cross Paths: Neuroplasticity-Informed ACL Rehabilitation that Includes Cross-Education.

Tibor Hortobágyi, Dustin R Grooms, Márk Váczi, Leila Bogdán, Rubén Lara Gómez, Tibor Mintál, Gergely Orsi, Nicola A Maffiuletti, Justin W Andrushko, Jonathan P Farthing

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In one paragraph

Article in Sports medicine - open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tibor HortobágyiDepartment of Human Movement Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. t.hortobagyi@umcg.nl.ORCID http://orcid.org/0000-0002-5731-6423
Dustin R GroomsOhio Musculoskeletal & Neurological Institute (OMNI), Ohio University, Athens, OH, USA.
Márk VácziDepartment of Kinesiology, Hungarian University of Sports Science, Budapest, Hungary.
Leila BogdánDepartment of Kinesiology, Hungarian University of Sports Science, Budapest, Hungary.
Rubén Lara GómezDepartamento de Fisioterapia, Facultad de Ciencias de la Salud, Universidad de Málaga, Málaga, Spain.
Tibor MintálSports Medicine Center, Medical School, University of Pécs, Pécs, Hungary.
Gergely OrsiDepartment of Neurology, Medical School, University of Pécs, Pécs, Hungary.
Nicola A MaffiulettiHuman Performance Lab, Schulthess Klinic, Zurich, Switzerland.
Justin W Andrushko *Department of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, Tyne and Wear, UK.
Jonathan P Farthing *College of Kinesiology, University of Saskatchewan, Saskatoon, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of anterior cruciate ligament (ACL) rehabilitation following reconstruction surgery is sub-optimal and the return-to-sport criteria are inconsistent. We examine the hypothesis that the dysfunctional neuroplasticity induced by an ACL injury could be resolved faster when cross-education is combined with innovative paradigms incorporating visual-cognitive tasks to reduce attentional compensation. We posit that the priming effects could be amplified if therapists combined higher force, eccentric based cross-education exercises with visual-cognitive dual-tasking. The overlapping nature of neuroplasticity after an ACL injury and that induced by cross education may provide a pathway to not only address the mechanical muscle strength deficits associated with injury, but the underlying neurological deficits as well. We provide a practical guide to how neuroplasticity-informed ACL rehabilitation that includes cross-education might accelerate recovery from an ACL injury and the subsequent reconstruction surgery.

Indexed as

Anterior cruciate ligamentCross-educationNeuroplasticityRehabilitation

Identifiers

PMID41663845
PMCPMC12886690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.