Article in EMBO reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors.
Justin BodnerDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.ORCID 0000-0001-7369-7724
Pranathi VadlamaniDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Alexander S LeeDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.ORCID 0000-0001-6214-1990
Kathryn A HelminDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.ORCID 0009-0006-8857-9943
Qianli LiuDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.ORCID 0000-0002-7629-5648
Almira E PrataseniaDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.ORCID 0009-0007-0273-8614
Maria M A HorstDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Sudharsana RavisankarDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Sakshi KhuranaDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.ORCID 0000-0003-1865-7820
Marc L MendilloDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Benjamin D SingerDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.ORCID 0000-0001-5775-8427
Shashank SrivastavaDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Daniel R FoltzDepartment of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA. dfoltz@northwestern.edu.ORCID 0000-0001-7423-6188
Funding
Technology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHARD G WUNDERINK · 2018 to 2026
$24.7M
The Cell Phenotyping and Mouse CoreP01HL154998 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2021 to 2026
$18.9M
Mechanisms of regulatory T cell-mediated recovery from severe viral pneumoniaR01HL149883 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Benjamin David Singer · 2020 to 2026
$4.1M
The role of the nucleolus in human genome organization in normal and disease statesU01CA260699 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FOLTZ, DANIEL RICHARD, HUANG, SUI · 2020 to 2024
$3.3M
Histone chaperone networks for new and evicted histonesR01GM143638 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI FOLTZ, DANIEL RICHARD · 2021 to 2024
$1.5M
Epigenetic modifiers of regulatory T cell function following viral pneumoniaR01HL153122 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SINGER, BENJAMIN DAVID · 2021 to 2021
$63k
HHS | NIH | National Cancer Institute (NCI) U01CA260699HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL149883HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL153122HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL154998HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI135964HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI181102HHS | NIH | National Institute of General Medical Sciences (NIGMS) R01GM143638HHS | NIH | National Institute on Aging (NIA) AG049665NHLBI NIH HHS P01 HL154998NHLBI NIH HHS R01 HL149883NHLBI NIH HHS R01 HL153122NIAID NIH HHS U19 AI135964
6 · The paper itself
Abstract
Proper histone gene expression is critical for cell viability and maintenance of genomic integrity. Multiple histone genes are organized into three genomic loci that encode replication-coupled core and linker histones. Histone gene expression and transcript processing are orchestrated in the histone locus body (HLB) within the nucleus. Here, we identify human CRAMP1 as a selective regulator of the linker histone H1 expression. Human CRAMP1 is recruited to the HLB in RPE1
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Human CRAMP1 specifically promotes the expression of histone H1 genes. · full record | OpenQuestion