Evidence map›Paper›PMID 41663756›Full record

ReviewApoptosis : an international journal on programmed cell death2026

Cell adhesion molecules as emerging regulators of ferroptosis: mechanisms and therapeutic opportunities in cancer.

Shiwen Liu, Li Fang, Haoran Suo, Sasa Chen, Linglong Yin, Xiong Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Apoptosis : an international journal on programmed cell death, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shiwen Liu *Key Laboratory of Clinical Precision Pharmacy of Guangdong Higher Education Institutes, The First Affiliated Hospital, Guangdong Pharmaceutical University, Guangzhou, 510699, Guangdong, China.
Li Fang *Key Laboratory of Clinical Precision Pharmacy of Guangdong Higher Education Institutes, The First Affiliated Hospital, Guangdong Pharmaceutical University, Guangzhou, 510699, Guangdong, China.
Haoran SuoKey Laboratory of Clinical Precision Pharmacy of Guangdong Higher Education Institutes, The First Affiliated Hospital, Guangdong Pharmaceutical University, Guangzhou, 510699, Guangdong, China.
Sasa ChenKey Laboratory of Clinical Precision Pharmacy of Guangdong Higher Education Institutes, The First Affiliated Hospital, Guangdong Pharmaceutical University, Guangzhou, 510699, Guangdong, China.
Linglong YinKey Laboratory of Clinical Precision Pharmacy of Guangdong Higher Education Institutes, The First Affiliated Hospital, Guangdong Pharmaceutical University, Guangzhou, 510699, Guangdong, China. linglongyll@gdpu.edu.cn.
Xiong LiKey Laboratory of Clinical Precision Pharmacy of Guangdong Higher Education Institutes, The First Affiliated Hospital, Guangdong Pharmaceutical University, Guangzhou, 510699, Guangdong, China. lixiong@gdpu.edu.cn.

Funding

Key Engineering Team, Discipline Cultivation Projects, Guangdong Pharmaceutical University 2024ZZ10National Natural Science Foundation of China 81572542National Natural Science Foundation of China 82503401
6 · The paper itself

Abstract

Ferroptosis represents an iron-dependent form of regulated cell death, distinguished by the accumulation of lipid peroxides. This process holds significant implications for tumor progression and resistance to therapeutic interventions. Cell adhesion molecules (CAMs), which facilitate interactions between cells and between cells and the extracellular matrix, have emerged as pivotal regulators of ferroptosis sensitivity within the cancerous milieu. Accumulating evidence underscores the capacity of CAMs to modulate key ferroptotic pathways. This includes the system Xc

Indexed as

Cell Adhesion MoleculesFerroptosisNeoplasmsAnimalsHumansIronLipid PeroxidationSignal TransductionCell Adhesion MoleculesIronCell adhesion moleculesFerroptosisIron metabolismTherapy resistance

Identifiers

PMID41663756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.