Evidence map›Paper›PMID 41663748›Full record

ArticleSurgical endoscopy2026

Clinical practice of indocyanine green fluorescence imaging in robotic liver surgery - a global expert survey.

Noa L E Aegerter, Christoph Kuemmerli, Adrian T Billeter, Caroline Berchtold, Felix Nickel, Cristiano Guidetti, Taiga Wakabayashi, Iswanto Sucandy, Brian K Goh, Mathieu D'Hondt and 8 more

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Noa L E AegerterClarunis, University Digestive Health Care Centre Basel, 4002 Basel, Basel, Switzerland.
Christoph KuemmerliClarunis, University Digestive Health Care Centre Basel, 4002 Basel, Basel, Switzerland.
Adrian T BilleterClarunis, University Digestive Health Care Centre Basel, 4002 Basel, Basel, Switzerland.
Caroline BerchtoldClarunis, University Digestive Health Care Centre Basel, 4002 Basel, Basel, Switzerland.
Felix NickelKlinik Und Poliklinik Für Allgemein-, Viszeral- Und Thoraxchirurgie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
Cristiano GuidettiHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Modena, Italy.
Taiga WakabayashiDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan.
Iswanto SucandyAdvent Health Medical Group, Digestive Health Institute at Florida Hospital Tampa/Minimally Invasive and Robotic Surgery, Tampa, FL, USA.
Brian K GohDepartment of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Center Singapore, Singapore, Singapore.
Mathieu D'HondtDepartment of Digestive and Hepatobiliary/Pancreatic Surgery, Groeninge Hospital, Kortrijk, Belgium.
Hugo Pinto MarquesHepato-Biliary-Pancreatic and Transplantation Centre, Curry Cabral Hospital, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Janina EdenClarunis, University Digestive Health Care Centre Basel, 4002 Basel, Basel, Switzerland.
Philipp DutkowskiClarunis, University Digestive Health Care Centre Basel, 4002 Basel, Basel, Switzerland.
Jason HawksworthDepartment of Surgery, Abdominal Organ Transplantation Division, Columbia University Irving Medical Center, New York, NY, USA.
Patrick StarlingerDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA.
Beat P MüllerClarunis, University Digestive Health Care Centre Basel, 4002 Basel, Basel, Switzerland.
Philip C MüllerClarunis, University Digestive Health Care Centre Basel, 4002 Basel, Basel, Switzerland. philip.mueller@clarunis.ch.ORCID http://orcid.org/0000-0001-8317-3449
Robotic Liver Surgery Expert Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndocyanine green (ICG) fluorescence imaging is increasingly incorporated into robotic liver resections (RLR), yet clinical practice regarding timing, dosage, and staining techniques is divergent. This international expert survey aimed to characterize current practices for ICG in RLR.

methodsExperts in RLR were invited to participate based on surgical volume (experience of

resultsSeventy experts from 19 countries completed the survey, corresponding to an 88% response rate. Centers performed a median of 180 annual liver resections, including 55 RLR. Most experts used ICG (96%) during RLR. Anatomical demarcation (91%), tumor localization (60%), and biliary anatomy assessment (60%) were the most frequent indications. 60% of experts use preoperative ICG, while intraoperative ICG is mainly administered for demarcation (67%) and biliary tract visualization (40%). Considerable heterogeneity exists in dosage, timing, and staining techniques, particularly in cirrhotic livers and for tumor localization. 53% of the experts had standard operating procedures, whereas 64% expressed the need for a higher degree of standardization. Reported benefits of ICG use included improved anatomical orientation, margin assessment, lesion detection, and support during complex resections. Perceived limitations included background fluorescence, tissue penetration and variable staining in diseased parenchyma. 80% anticipated improved outcomes with combined ICG and three-dimensional image-guidance.

conclusionICG fluorescence is widely used in RLR and is an important cornerstone for precision-guided robotic liver surgery. Standardized clinical practice guidelines, structured training, and technological improvements in imaging and navigation systems are claimed to optimize its clinical use.

Indexed as

Coloring AgentsHepatectomyIndocyanine GreenOptical ImagingPractice Patterns, Physicians'Robotic Surgical ProceduresHumansLiverLiver NeoplasmsSurveys and QuestionnairesColoring AgentsIndocyanine GreenFireflyIndocyanine greenLiver resectionRobotic liver surgery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.