ArticleScientific reports2026
Exploring the chemical space around Cannabis sativa L. leaves as a source of bioactive compounds of pharmaceutical interest.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Prenylated apigenin derivatives from Cannabis sativa L.: isolation, biosynthesis, and anti-inflammatory properties.Journal of cannabis research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
In the field of Cannabis sativa L. derived products, the attention has been usually focused on plant inflorescences as a source of cannabinoids, with stems and seeds also utilized, while leaves are typically discharged. Although previous studies have examined the composition of C. sativa leaves to evaluate their antioxidant potential, their full value remains largely unknown. In this perspective, this study aims to reveal the hidden potential of C. sativa leaves to reposition them from a waste material to an alternative source of bioactive compounds. To this purpose, the leaves of four non-psychotropic C. sativa (hemp) varieties, including a cannabinoid-free one, were comprehensively characterized for their composition for the first time. The most relevant outcome of the present work was the first identification and characterization of squalene in hemp leaves, along with the development of a suitable extraction and analytical method for this bioactive triterpenoid. Among cannabinoids, cannabinoic acids were the most abundant compounds, complemented by the detection of several minor compounds having either the cannabidiol (CBD) or cannabigerol (CBG) scaffold. As for the other chemical constituents, cannflavins were the predominant non-cannabinoid phenolic compounds. The analysis also addressed to policosanols and terpenes, revealing some variety-specific volatile compounds, beside the most common ones. Overall, hemp leaves showed a rich chemical composition to be exploited in the pharmaceutical field, perfectly aligning with a circular economy perspective.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.