ArticleBDJ open2026
Linking lungs and gums: a meta-analysis of periodontitis prevalence and severity in chronic obstructive pulmonary disease.
Article in BDJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Oral health in chronic obstructive pulmonary disease: are physicians prepared to integrate it into routine care?Frontiers in medicine · 2026Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimChronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder associated with chronic inflammation and airflow limitation. Periodontitis shares common risk factors with COPD, such as smoking. This meta-analysis evaluates the prevalence and severity of periodontitis in COPD patients by assessing periodontal parameters, including probing depth (PD), clinical attachment loss (CAL), and bleeding on probing (BOP).
methodsA systematic search of electronic databases identified clinical studies reporting periodontitis in COPD patients. Studies with clear diagnostic criteria for both conditions were included. Data extraction was conducted using RAYYAN software, and study quality was assessed using the Newcastle-Ottawa Scale (NOS). A random-effects meta-analysis was performed in R Studio, with heterogeneity assessed using the I² statistic. To assess the robustness of the findings, a leave-one-out sensitivity analysis was conducted for CAL and PD. Publication bias was examined using the Trim and Fill method. Additionally, stratified subgroup analyses were performed based on smoking status and study design to explore potential sources of heterogeneity. Certainty of evidence was assessed using GRADE.
resultsA total of 41 studies were included. Periodontitis prevalence in COPD patients was 35%, significantly higher than in non-COPD controls. COPD patients exhibited greater periodontal destruction, with increased CAL (0.68 [0.37;0.98]) deeper PD (0.72 [0.12; 1.31]), and BOP (1.49 [0.19;2.79]). However, the certainty of this evidence was rated as low to very low.
conclusionCOPD patients have a higher prevalence of periodontitis and worse periodontal parameters. While our meta-analysis suggests an association, the overall certainty of evidence is low. These findings should therefore be interpreted with caution. Future high-quality prospective studies are essential to confirm this relationship and inform clinical practice.
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Registered trials
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