Evidence map›Paper›PMID 41663352›Full record

ArticleActa neuropsychiatrica2026

Investigation of leptin and leptin receptor gene polymorphisms in schizophrenia: further support for an association with attempted suicide.

Hasan Mervan Aytac, Yasemin Oyaci, Eren Aytac, Mustafa Pehlivan, Huseyin Sehit Burhan, Furkan Bahadir Alptekin, Sacide Pehlivan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropsychiatrica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hasan Mervan AytacInstitute of Graduate Studies in Health Sciences, Istanbul Universityhttps://ror.org/03a5qrr21, Istanbul, Türkiye.ORCID https://orcid.org/0000-0002-1053-6808
Yasemin OyaciDepartment of Basic Sciences, Istanbul Nisantasi University, Istanbul, Türkiye.
Eren AytacPsychiatry Unit, Varto State Hospital, Mus, Türkiye.
Mustafa PehlivanDepartment of Hematology, Basaksehir Cam and Sakura City Hospital, Istanbul, Türkiye.
Huseyin Sehit BurhanDepartment of Psychiatry, Basaksehir Cam and Sakura City Hospital, University of Health Scienceshttps://ror.org/05grcz969r, Istanbul, Türkiye.
Furkan Bahadir AlptekinDepartment of Psychiatry, Basaksehir Cam and Sakura City Hospital, University of Health Scienceshttps://ror.org/05grcz969r, Istanbul, Türkiye.
Sacide PehlivanInstitute of Graduate Studies in Health Sciences, Istanbul Universityhttps://ror.org/03a5qrr21, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate leptin (

methodsThe study included 120 patients with schizophrenia and 130 healthy volunteers. Sociodemographic characteristics, suicidal behavior, and symptom severity were assessed using data collection forms. Gene polymorphisms were analyzed from DNA samples using the polymerase chain reaction-restriction fragment length polymorphism.

resultsThe

conclusionOur findings suggest that

Indexed as

LeptinReceptors, LeptinSchizophreniaSuicide, AttemptedAdultCase-Control StudiesFemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedPolymorphism, Single NucleotideLEP protein, humanLEPR protein, humanLeptinReceptors, Leptinleptinleptin receptorschizophreniasingle nucleotide polymorphismsuicide attempt

Identifiers

PMID41663352
PMCPMC13130374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.