Evidence map›Paper›PMID 41663322›Full record

ArticleInternational wound journal2026

Assessing the Clinical and Cost Effectiveness of Dialkylcarbamoylchloride (DACC) Coated Post-Operative Dressings Versus Standard Care in the Prevention of Surgical Site Infection in Clean or Clean-Contaminated, Vascular Surgery (DRESSINg Trial): Study Protocol for a Multicentre Randomised Controlled Trial.

Arthur Jun Ming Lim, Ross Lathan, Joshua Totty, Louise Hitchman, Joseph Cutteridge, Kate Adams, Phillipa Burns, Judith Long, Chao Huang, Leanne Cox and 3 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in International wound journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Arthur Jun Ming LimAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
Ross LathanAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
Joshua TottyAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
Louise HitchmanAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
Joseph CutteridgeAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
Kate AdamsDepartment of Infectious Diseases, Hull University Teaching Hospitals NHS Trust, Hull, UK.
Phillipa BurnsDepartment of Infectious Diseases, Hull University Teaching Hospitals NHS Trust, Hull, UK.
Judith LongAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
Chao HuangCentre for Clinical Sciences, Hull York Medical School, Hull, UK.ORCID https://orcid.org/0000-0002-3627-7218
Leanne CoxAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
Daniel CarradiceAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
George SmithAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.
Ian ChetterAcademic Vascular Surgical Unit, Hull York Medical School, Hull, UK.

Funding

Healthcare Infection Society MRG-2022-003
6 · The paper itself

Abstract

Surgical site infections (SSI) in vascular surgery have a huge impact on patients' morbidity and mortality and healthcare systems worldwide. Dialkylcarbamoylchoride (DACC) is a synthetically produced material that can irreversibly bind and inactivate bacteria that exhibit cell-surface hydrophobicity (CSH). The DACC in the Reduction of Surgical Site Infection (DRESSINg) trial is a multicentre randomised controlled trial which aims to assess the effectiveness of DACC-coated post-operative dressings in the prevention of SSI in vascular surgery. Seven hundred and eighteen participants undergoing clean or clean-contaminated lower limb vascular surgery will be randomised in a 1:1 ratio to either DACC-coated dressings or standard dressings for their postoperative wounds. The primary outcome is the incidence of SSI defined by the Centers for Disease Control and Prevention (CDC) criteria or total ASEPSIS score of 21 or more within 30 days of surgery. The secondary outcomes include satisfactory wound healing with a total ASEPSIS score of 10 or less, quality of life pre and post surgery, Bluebelle wound healing scores, resource use and financial (£), and environmental (KgCO2e) cost analyses. This multicentre randomised controlled trial will provide level 1 evidence on the effectiveness of preventing SSI in lower limb vascular surgery.

Indexed as

BandagesPostoperative CareSurgical Wound InfectionVascular Surgical ProceduresAdultAgedCost-Benefit AnalysisCost-Effectiveness AnalysisFemaleHumansMaleMiddle AgedMulticenter Studies as TopicRandomized Controlled Trials as TopicWound HealingDACCDialkylcarbamoylchloridesurgical wound infectionvascular surgical procedures

Identifiers

PMID41663322
PMCPMC12885752

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.