Evidence map›Paper›PMID 41663194›Full record

ReviewZhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi2026

[Research advances in clonal hematopoiesis associated with hematopoietic stem cell transplantation].

Z Jin, Y Y Chen, M Shan, Y Xu

Abstract readReviewEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Review in Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Z JinThe First Affiliated Hospital of Soochow University, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis Under Ministry of Health, Institute of Blood and Marrow Transplantation, Soochow University, Suzhou 215006, China.
Y Y ChenThe First Affiliated Hospital of Soochow University, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis Under Ministry of Health, Institute of Blood and Marrow Transplantation, Soochow University, Suzhou 215006, China.
M ShanThe First Affiliated Hospital of Soochow University, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis Under Ministry of Health, Institute of Blood and Marrow Transplantation, Soochow University, Suzhou 215006, China.
Y XuThe First Affiliated Hospital of Soochow University, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis Under Ministry of Health, Institute of Blood and Marrow Transplantation, Soochow University, Suzhou 215006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the development of high-throughput sequencing technology, clonal hematopoiesis has received extensive attention in the research of cardiovascular, cerebrovascular, and hematological diseases. Hematopoietic stem cell transplantation (HSCT) is an effective treatment for malignant hematological diseases and has considerably improved the survival rate of patients. However, the exact mechanisms underlying the adverse outcomes, such as graft-versus-host disease, treatment-related myeloid neoplasms, and disease recurrence after transplantation, have not been fully elucidated. Recent studies have shown that mutation genes related to clonal hematopoiesis (such as DNMT3A and PPM1D) may be closely related to the adverse prognosis of HSCT. The present article systematically summarizes the genetic factors, inducements, research progress, and impact on patient prognosis of HSCT-related clonal hematopoiesis, providing a theoretical basis for further exploration of the related mechanisms and optimization of HSCT regimens.

Indexed as

Clonal HematopoiesisHematopoietic Stem Cell TransplantationDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3AHumansMutationPrognosisProtein Phosphatase 2CDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanPPM1D protein, humanProtein Phosphatase 2C

Identifiers

PMID41663194
PMCPMC13463341

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.