Evidence map›Paper›PMID 41663187›Full record

ArticleZhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi2026

[Clinical characteristics of RUNX1-mutated acute myeloid leukemia patients].

Y X Dong, W J Dai, W Q Zhang, B B Xie, Q Zhang, Y Dong, H Qin, Z M Zhai, Q S Tao, L L Tao

Abstract readEnglish Abstract
In one paragraph

Article in Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Y X DongDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.
W J DaiDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.
W Q ZhangDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.
B B XieDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.
Q ZhangDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.
Y DongDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.
H QinDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.
Z M ZhaiDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.
Q S TaoDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.
L L TaoDepartment of Hematology and the Diagnosis and Treatment Center for Hematologic Diseases of the Second Affiliated Hospital of Anhui Medical University, Anhui Medical University Hematology Research Center, Hefei 230601, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We retrospectively analyzed the RUNX1 mutation status and clinical characteristics of 323 newly diagnosed acute myeloid leukemia (AML) patients treated in the Second Affiliated Hospital of Anhui Medical University from February 2018 to May 2023. The mutation rate of RUNX1 in AML patients was 11.5% with a median mutation frequency of 40.4%. RUNX1 mutations often coexisted with other mutations, such as ASXL1, but were mutually exclusive with NPM1 mutations. AML patients with RUNX1 mutations were older (median age: 65

Indexed as

Core Binding Factor Alpha 2 SubunitLeukemia, Myeloid, AcuteMutationAdolescentAdultAgedFemaleHumansMaleMiddle AgedNucleophosminPrognosisRepressor ProteinsRetrospective StudiesYoung AdultCore Binding Factor Alpha 2 SubunitNPM1 protein, humanNucleophosminRepressor ProteinsRUNX1 protein, human

Identifiers

PMID41663187
PMCPMC13463342

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.