Evidence map›Paper›PMID 41662598›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2026

Correlation of Hypertension With Adverse Outcomes Following Total Hip Arthroplasty: A Matched Cohort Analysis.

Ismail Ajjawi, Anshu Jonnalagadda, Jonathan N Grauer

Abstract read
In one paragraph

Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ismail AjjawiFrom the Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT.
Anshu Jonnalagadda
Jonathan N GrauerORCID 0000-0002-2626-7278

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTotal hip arthroplasty (THA) is a widely performed procedure. Despite its overall success, adverse outcomes have been associated with defined comorbidities. Hypertension (HTN), which affects a notable portion of the adult population, may be one such factor but has not been independently studied in this regard.

methodsTHA patients were abstracted from the 2010 to 2022 M165 Ortho PearlDiver Mariner Database. Adult patients with versus without HTN were matched 1:1 based on age, sex, and Elixhauser Comorbidity Index. Ninety-day adverse outcomes and 5-year implant survival rates were compared for the matched cohorts with multivariable analysis, adjusting for multiple comparisons.

resultsOf 851,605 THA patients identified, HTN was noted for 601,475 (70.6%). After matching, there were 148,946 patients with and the same number without HTN. Patients with HTN were at independently greater odds of most individual adverse outcomes assessed, any adverse events (odds ratio [OR] 2.18), serious adverse events (OR 2.19), minor adverse events (OR 2.26), and readmissions (OR 1.52) (P < 0.001 for each). Furthermore, the 5-year implant survival rate was mildly lower in HTN group (96.5% versus 97.5%, P < 0.001). DISCUSSION: The current, large-cohort study identified HTN to be diagnosed for more than half of patients undergoing THA. The clear correlation of HTN with many adverse outcomes and mildly (but statistically) lower 5-year implant survival highlights the need for further consideration of this variable. Although there could be other confounding factors that may not have been fully controlled, those with HTN are clearly an "at-risk" group.

Indexed as

Arthroplasty, Replacement, HipHypertensionPostoperative ComplicationsAgedCohort StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesRisk Factors

Identifiers

PMID41662598
PMCPMC12879957

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.