Evidence map›Paper›PMID 41662454›Full record

ArticleCirculation2026

Cardiomyocyte-Specific modRNA-Induced FoxM1 Overexpression Promotes Recovery From Myocardial Infarction in Adult Mammals.

Yalin Wu, Thanh Nguyen, Yongyu Wang, Yang Zhou, Jianli Zhao, Yajing Wang, Gregory P Walcott, Daniel J Garry, Yuji Nakada, Jianyi Zhang

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yalin WuDepartments of Biomedical Engineering (Y. Wu, T.N., Yongyu Wang, Y.Z., J. Zhao, Yajing Wang, G.P.W., Y.N., J. Zhang), University of Alabama at Birmingham.ORCID 0009-0003-8772-6671
Thanh NguyenDepartments of Biomedical Engineering (Y. Wu, T.N., Yongyu Wang, Y.Z., J. Zhao, Yajing Wang, G.P.W., Y.N., J. Zhang), University of Alabama at Birmingham.ORCID 0000-0002-8440-1594
Yongyu WangDepartments of Biomedical Engineering (Y. Wu, T.N., Yongyu Wang, Y.Z., J. Zhao, Yajing Wang, G.P.W., Y.N., J. Zhang), University of Alabama at Birmingham.
Yang ZhouDepartments of Biomedical Engineering (Y. Wu, T.N., Yongyu Wang, Y.Z., J. Zhao, Yajing Wang, G.P.W., Y.N., J. Zhang), University of Alabama at Birmingham.ORCID 0000-0002-9217-5208
Jianli ZhaoDepartments of Biomedical Engineering (Y. Wu, T.N., Yongyu Wang, Y.Z., J. Zhao, Yajing Wang, G.P.W., Y.N., J. Zhang), University of Alabama at Birmingham.ORCID 0000-0003-4662-2940
Yajing WangDepartments of Biomedical Engineering (Y. Wu, T.N., Yongyu Wang, Y.Z., J. Zhao, Yajing Wang, G.P.W., Y.N., J. Zhang), University of Alabama at Birmingham.ORCID 0000-0002-6358-6948
Gregory P WalcottDepartments of Biomedical Engineering (Y. Wu, T.N., Yongyu Wang, Y.Z., J. Zhao, Yajing Wang, G.P.W., Y.N., J. Zhang), University of Alabama at Birmingham.ORCID 0000-0002-9807-7422
Daniel J GarryDepartment of Medicine, School of Medicine, University of Minnesota, Minneapolis (D.J.G.).ORCID 0000-0002-8970-7365
Yuji NakadaDepartments of Biomedical Engineering (Y. Wu, T.N., Yongyu Wang, Y.Z., J. Zhao, Yajing Wang, G.P.W., Y.N., J. Zhang), University of Alabama at Birmingham.ORCID 0000-0001-8229-4775
Jianyi ZhangDepartments of Biomedical Engineering (Y. Wu, T.N., Yongyu Wang, Y.Z., J. Zhao, Yajing Wang, G.P.W., Y.N., J. Zhang), University of Alabama at Birmingham.ORCID 0000-0002-3955-6554

Funding

Project 3 - Role of Proline Metabolism in Regulation of Mammalian Cardiomyocyte ProliferationP01HL160476 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jianyi Zhang · 2022 to 2026
$13.1M
Integrated Cellular and Tissue Engineering for Ischemic Heart DiseaseU01HL134764 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BURSAC, NENAD, KAMP, TIMOTHY J. · 2016 to 2022
$7.7M
Supplement of HL131017: Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytesR01HL131017 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SERPOOSHAN, VAHID, ZHANG, JIANYI · 2016 to 2025
$5.8M
Endogenous and exogenous mechanisms that promote myocardial remuscularization in post infarction LV remodelingR01HL114120 · NHLBI · UNIVERSITY OF MINNESOTA · PI ZHANG, JIANYI · 2012 to 2021
$5.6M
Induction of Cardiomyocyte Proliferation via Transient Expression of Cell Cycle Factors as a Promising Therapy for Heart FailureR01HL147921 · NHLBI · UNIVERSITY OF LOUISVILLE · PI Tamer M A Mohamed, Jonathan Satin · 2020 to 2026
$5.3M
Deciphering the Neonatal Cardiac Regenerative Potential and Regulators in Large AnimalsR01HL149137 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SADEK, HESHAM, ZANGI, LIOR · 2019 to 2022
$2.5M
Defining the major signaling mechanism which controls spontaneous cardiomyocyte proliferation in the Neonatal StageR01HL178610 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI Tamer M A Mohamed · 2025 to 2026
$1.5M
NHLBI NIH HHS P01 HL160476NHLBI NIH HHS R01 HL114120NHLBI NIH HHS R01 HL131017NHLBI NIH HHS R01 HL147921NHLBI NIH HHS R01 HL149137NHLBI NIH HHS R01 HL178610NHLBI NIH HHS U01 HL134764
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cell cycleheart failuremyocardial infarctionmyocytes, cardiac

Identifiers

PMID41662454
PMCPMC12888790

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.