Evidence map›Paper›PMID 41662349›Full record

ArticleNeonatology2026

Home-Based Transcutaneous Bilirubin Screening and Telemedicine Reduce Neonatal Referrals.

Sagee Nissimov, Nili Haas, Sonia Habib, Batia Madjar, Deena R Zimmerman, Ariela Hazan, Sharon Daniel, Matitiahu Berkovitch, Elkana Kohn

Abstract read
In one paragraph

Article in Neonatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sagee NissimovDepartment of Neonatology, Shamir Medical Center, Zerifin, Israel, sageen@shamir.gov.il.
Nili HaasFamily Health Centers, Haifa and Western Galilee District Health Office, Public Health Services, Israeli Ministry of Health, Haifa, Israel.
Sonia HabibHaifa and Western Galilee District Health Office, Public Health Services, Israeli Ministry of Health, Haifa, Israel.
Batia MadjarFamily Health Centers, Haifa and Western Galilee District Health Office, Public Health Services, Israeli Ministry of Health, Haifa, Israel.
Deena R ZimmermanMaternal Child and Adolescent Department, Public Health Directorate, Ministry of Health, Jerusalem, Israel.
Ariela HazanClinical Pharmacology and Toxicology Unit, Shamir Medical Center, Zerifin, Israel.
Sharon DanielDepartment of Epidemiology, Biostatistics and Community Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Matitiahu BerkovitchGray Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel.
Elkana KohnClinical Pharmacology and Toxicology Unit, Shamir Medical Center, Zerifin, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: Neonatal jaundice is a leading cause of early post-discharge referrals. Community follow-up commonly relies on visual assessment and clinic-based evaluation, generating avoidable visits. Scalable home pathways that maintain safety are needed. We evaluated a nurse-led home pathway that integrates transcutaneous bilirubin (TcB) screening with targeted pediatric teleconsultation.

methodsA prospective before-after study was conducted within routine nurse-led home visits for eligible infants (firstborn or preterm) ≥35 weeks of gestation. A 3-month pre-intervention phase (usual visual assessment) was compared with a 9-month intervention using TcB-guided thresholds and teleconsultation via a secure digital platform. The primary analysis targeted infants who, under usual care, would be referred ("baseline-eligible"), estimating the absolute difference in referral at the home visit. Secondary outcomes were agreement between clinical cues and TcB, teleconsultation utilization, and phototherapy requirement.

resultsA total of 1,236 infants were enrolled (157 pre-intervention; 1,079 intervention). Among baseline-eligible infants (n = 840), 152 (18.1%) were referred; thus, 688/840 (81.9%) potential referrals were avoided (absolute reduction 81.9%; 95% CI 79.2-84.4; NNR 1.22, 95% CI 1.19-1.26). TcB identified all infants requiring phototherapy (4/1,079; 0.4%) within 14 days. Agreement between clinical cues and TcB-defined need for follow-up was slight (weighted κ = 0.075; 95% CI 0.059-0.091). The reduction in referrals corresponded to an absolute decrease of 0.67 visits per infant.

conclusionsA nurse-led, digitally supported home pathway that integrates TcB screening and targeted teleconsultation substantially reduces unnecessary neonatal referrals, with no missed cases requiring phototherapy. This pragmatic precision-triage model is implementable within existing community services and can relieve post-discharge system burden while preserving safety. </p>.

Indexed as

BilirubinJaundice, NeonatalNeonatal ScreeningReferral and ConsultationFemaleHumansInfant, NewbornInfant, PrematureMalePhototherapyProspective StudiesRemote ConsultationTelemedicineBilirubinHome care servicesNeonatal jaundiceTelemedicineTranscutaneous bilirubin

Identifiers

PMID41662349
PMCPMC13078750

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.