Evidence map›Paper›PMID 41662326›Full record

ArticleCardiology2026

Comprehensive Assessment of Left Ventricular Function and Exercise Endurance in Patients with Hypertrophic Cardiomyopathy: The Combined Application of Left Ventricular Pressure-Strain Loop and Cardiopulmonary Exercise Testing.

Yufen Lin, Shuhong Hou, Jianting Lin, Tingting Zhang, Bo Wu, Qiaolian Wu, Sihua Qiu, Jinghui Chen, Dongping Chen, Junlong Huang

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Article in Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yufen LinDepartment of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Shuhong HouDepartment of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Jianting LinDepartment of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Tingting ZhangDepartment of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Bo WuDepartment of Cardiovascular Medicine, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Qiaolian WuDepartment of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Sihua QiuDepartment of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Jinghui ChenDepartment of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Dongping ChenDepartment of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China, fjchendp@163.com.
Junlong HuangDepartment of Ultrasound, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China, 17306070298@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: This study aims to assess left ventricular (LV) function and exercise endurance in patients with hypertrophic cardiomyopathy (HCM) using a combination of left ventricular pressure-strain loop (LV-PSL) and cardiopulmonary exercise testing (CPET) and to explore the correlation of the maximum left ventricular wall thickness (MWT) with clinical, echocardiographic, and CPET parameters.

methodsA total of 55 patients with nonobstructive HCM, diagnosed between January 2022 and March 2023 at Longyan First Affiliated Hospital of Fujian Medical University, were included, along with 55 healthy volunteers as a control group. Two-dimensional ultrasound speckle tracking technology was used to obtain global longitudinal strain (GLS), longitudinal strain peak time dispersion (PSD), as well as the myocardial global work index (GWI), myocardial global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE). The differences in these parameters were compared between the two groups before and after CPET. CPET was used to measure peak oxygen consumption (Peak VO

resultsCompared to the control group, the HCM group showed significant reductions in GLS, GWI, GCW, and GWE, while GWW and PSD were significantly increased, with statistical significance (p < 0.05). Peak VO

conclusionLV-PSL combined with CPET is effective in early detection of LV function and exercise endurance impairment in HCM patients, providing valuable information for clinical decision-making. </p>.

Indexed as

Cardiomyopathy, HypertrophicExercise ToleranceVentricular Function, LeftAdultCase-Control StudiesEchocardiographyExercise TestFemaleGlobal Longitudinal StrainHeart VentriclesHumansMaleMiddle AgedOxygen ConsumptionCardiopulmonary exercise testingExercise enduranceHypertrophic cardiomyopathyMyocardial work

Identifiers

PMID41662326
PMCPMC13008389

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.