Evidence map›Paper›PMID 41662222›Full record

ArticlePloS one2026

The 83 symptoms of tinnitus: Content overlap of commonly used scales for tinnitus burden.

Milena Engelke, Jorge Piano Simões, Berthold Langguth, Winfried Schlee, Laura Basso

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Milena EngelkeDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Jorge Piano SimõesDepartment of Psychology, Health and Technology, University of Twente, Enschede, Netherlands.ORCID https://orcid.org/0000-0003-3397-2319
Berthold LangguthDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Winfried SchleeDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.ORCID https://orcid.org/0000-0001-7942-1788
Laura BassoDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.ORCID https://orcid.org/0000-0002-6517-7902

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical management of tinnitus remains challenging due to unclear etiology and diverse phenotypic manifestations. To quantify its associated burden, a variety of patient-reported outcome measures (PROMs) are used. This study aims to comprehensively evaluate the content overlap of items between eight PROMs commonly used in tinnitus research.

methodsA two-stage, blinded multi-rater process was used to analyze the content of all 199 items from the International Tinnitus Inventory (ITI), Subjective Tinnitus Severity Scale (STSS), Tinnitus Functional Index (TFI), Tinnitus Handicap Inventory (THI), Tinnitus Handicap Questionnaire (THQ), Tinnitus Primary Function Questionnaire (TPFQ), Tinnitus Questionnaire (TQ), and Tinnitus Reaction Questionnaire (TRQ). The Jaccard Index was used to measure pairwise content overlap between scales.

resultsThe analysis revealed 83 distinct symptoms. "Concentration" was the most frequently captured symptom (in seven scales), whereas 41 symptoms (49.4%) were unique to one scale. The TQ exhibited the highest number of unique symptoms (52.5%), while the THI had the least (4%). The Jaccard Index identified very weak/weak scale overlap between the PROMs. The highest overlap was observed between TFI and THI (0.35). The TFI had the highest mean overlap (0.26), coming closest to the content measured by all other PROMs.

conclusionThe results demonstrate high heterogeneity and limited content overlap among tinnitus burden PROMs, similar to other conditions. The findings suggest that tinnitus burden is not measured as a unified construct across questionnaires, thus, researchers and clinicians should carefully consider the specific symptoms measured when selecting instruments for treatment evaluation and comparison.

Indexed as

TinnitusAdultAgedFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresSeverity of Illness IndexSurveys and QuestionnairesSymptom Burden

Identifiers

PMID41662222
PMCPMC12885300

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