ArticlePLOS mental health2025
Developing programme theory for a place-based, systems change approach to adolescent mental health: A developmental realist evaluation.
Article in PLOS mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Addressing the social determinants of youth mental health in Newham and Northern Devon: reflections on co-design and systems change.BMC public health · 2026Article
- An adaptive, youth-centred co-design methodology: place-based co-design centring youth and community participation.Research involvement and engagement · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
Kailo is a prevention framework that supports local communities to co-design evidence-informed strategies to address the social determinants of adolescent mental health and wellbeing. Similar place-based initiatives exist internationally but research into the mechanisms of change and contextual drivers is limited. Understanding how and why Kailo functions is crucial for refining the framework before it is implemented in different contexts and for informing the focus of an impact evaluation. We conducted a developmental, realist-informed evaluation to investigate how and why the Kailo framework functions, for whom and under what circumstances. The first phase of the evaluation involved a rapid realist review, observations of key processes, key informant interviews, and document analysis. These methods informed the development of a series of initial programme theories. The second phase involved testing and refining these initial programme theories through further interviews and focus groups with key informants. A realist dialogic approach was used throughout, and our work was supported by two Young People's Advisory Groups who provided input on both the approach and theory generation. We generated a series of programme theories that shed light on the underlying mechanisms through which the Kailo framework works, the ways in which context acts as a catalyst for change, and the outcomes prioritised. These programme theories fall into six themes: 1) Alignment; 2) Time; 3) Credibility; 4) Accessible Spaces; 5) Building a Shared Understanding/Mission; and 6) Creating Hope that Change is Possible. Our study has informed the further development of the Kailo framework and lays the groundwork for a subsequent contributory impact evaluation to assess how Kailo contributes to system-level change and, ultimately, improvements in adolescent mental health and wellbeing. The programme theories generated also contribute to a wider understanding of how complex place-based approaches may function.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.