Evidence map›Paper›PMID 41661928›Full record

ArticlePLOS mental health2025

Quality of life among leprosy patients: An analysis of associated factors.

Alo Edin, Ziyad Towfik, Dejene Tesfaye, Abduselam Asefa, Abdulmalik Abdela Bushra, Ibsa Abdusemed Ahmed, Angefa Ayele

Abstract read
In one paragraph

Article in PLOS mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Quality of life, stigma, and mental health, in individuals affected by leprosy: a cross-sectional study.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alo EdinDepartment of Epidemiology, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.ORCID https://orcid.org/0000-0001-6977-2672
Ziyad TowfikDepartment of Psychiatry, Collage of Health and Medical Sciences, Haramaya University, Haramaya, Ethiopia.
Dejene TesfayeDepartment of Psychiatry, Collage of Health and Medical Sciences, Haramaya University, Haramaya, Ethiopia.
Abduselam AsefaDepartment of Psychiatry, Collage of Health and Medical Sciences, Haramaya University, Haramaya, Ethiopia.
Abdulmalik Abdela BushraEast Hararghe Zonal Health Department, Oromia Regional State, Harar, Ethiopia.ORCID https://orcid.org/0000-0002-0590-8689
Ibsa Abdusemed AhmedSchool of Public Health, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Angefa AyeleDepartment of Epidemiology, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.ORCID https://orcid.org/0000-0002-5308-862X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leprosy is accompanied by stigma and discrimination that significantly impact patients' quality of life. Previous studies in Ethiopia have focused primarily on demographic and disease-related aspects, neglecting mental health factors. Therefore, was aimed to assess quality of life and associated factors among leprosy patients in Eastern Ethiopia. An institutional-based cross-sectional study was conducted among 170 leprosy patients at Bisidimo General Hospital using the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire. Data were analyzed using STATA version 17, with multiple linear regression identifying associations between variables. Mean domain scores were: physical 53.03 ± 16.44, psychological 51.37 ± 13.10, social 44.95 ± 18.34, and environmental 57.10 ± 15.28. Depression, anxiety, comorbidity, stigma, and illness duration showed significant negative associations with quality of life domains. Income demonstrated positive associations across all domains. Additionally, poor social support negatively impacted the physical domain, while lifetime khat use negatively affected the social domain. Leprosy patients exhibited lower scores in social and psychological domains but higher scores in the environmental domain. Most factors affecting quality of life are preventable, suggesting the importance of programs that increase awareness, facilitate early treatment, and implement routine screening for mental health alongside physical health to improve patients' quality of life.

Identifiers

PMID41661928
PMCPMC12798199

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.