ArticlePLOS mental health2024
Moderation of the real-world effectiveness of smoking cessation aids by mental health conditions: A population study.
Article in PLOS mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Prevalence of Nicotine Pouch Use Among Youth and Adults in Great Britain-Analysis of Cross-Sectional, Nationally Representative Surveys.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- Article
- Scoping of Policy Impacts for Regulating E-cigarettes (SPIRE): findings from a data and decision analytic model mapping project.NIHR open research · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine whether the real-world effectiveness of popular smoking cessation aids differs between users with and without a history of mental health conditions.
designNationally-representative cross-sectional survey conducted monthly between 2016-17 and 2020-23.
settingEngland.
participants5,593 adults (2,524 with a history of ≥1 mental health conditions and 3,069 without) who had smoked regularly within the past year and had attempted to quit at least once in the past year.
main outcome measuresThe outcome was self-reported abstinence from quit date up to the survey. Independent variables were use of the following cessation aids during the most recent quit attempt: prescription nicotine replacement therapy (NRT), NRT over-the-counter, varenicline, bupropion, vaping products, face-to-face behavioural support, telephone support, written self-help materials, websites, hypnotherapy, Allen Carr's Easyway, heated tobacco products, and nicotine pouches. The moderator was history of diagnosed mental health conditions (yes/no). Covariates included sociodemographic characteristics, level of cigarette addiction, and characteristics of the quit attempt.
resultsRelative to those without, participants with a history of mental health conditions were significantly more likely to report using vaping products (38.8% [95%CI 36.7-40.8] vs. 30.7% [28.9-32.5]), prescription NRT (4.8% [3.9-5.7] vs. 2.7% [2.1-3.3]), and websites (4.0% [3.2-4.8] vs. 2.2% [1.6-2.7]). Groups did not differ significantly in their use of other aids. After adjusting for covariates and use of other cessation aids, those who used vaping products (OR = 1.92, 95%CI 1.61-2.30), varenicline (OR = 1.88, 95%CI 1.19-2.98), or heated tobacco products (OR = 2.33, 95%CI 1.01-5.35) had significantly higher odds of quitting successfully than those who did not report using these aids. There was little evidence that using other cessation aids increased the odds of successful cessation, or that the user's history of mental health conditions moderated the effectiveness of any aid.
conclusionsUse of vaping products, varenicline, or heated tobacco products in a quit attempt was associated with significantly greater odds of successful cessation, after adjustment for use of other cessation aids and potential confounders. There was no evidence to suggest the effectiveness of any popular cessation aid differed according to the user's history of mental health conditions.
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Registered trials
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