Evidence map›Paper›PMID 41661809›Full record

ArticlePLOS mental health2024

Early intervention model for treating mood and anxiety disorders: A realist mixed-methods hypothesis test of emerging adult recovery through the mechanism of agency.

Elizabeth Osuch, Evelyn Vingilis, Michael Wammes, Jazzmin Demy, Carolyn Summerhurst, Justin Arcaro

Abstract read
In one paragraph

Article in PLOS mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth OsuchLawson Health Research Institute, London, Ontario, Canada.ORCID https://orcid.org/0000-0001-5946-1862
Evelyn VingilisDepartment of Psychiatry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Michael WammesLawson Health Research Institute, London, Ontario, Canada.
Jazzmin DemyDepartment of Psychology, Faculty of Health, York University, Toronto, Ontario, Canada.
Carolyn SummerhurstLondon Health Sciences Center, London, Ontario, Canada.ORCID https://orcid.org/0009-0008-7802-018X
Justin ArcaroCollege of Medicine, American University of Antigua, University Park, Coolidge, Antigua & Barbuda.ORCID https://orcid.org/0009-0007-3526-8786

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early intervention treatment programs for mood and anxiety disorders are desperately needed since incidence of these is increasing. Evaluating such programs can identify which model components are helpful in providing improved outcomes. Realist evaluations discuss context-mechanism-outcome configurations to identify which interventions help whom, how, and under what circumstances. This study presents a realist configuration to evaluate an early intervention mood and anxiety program. The intervention involves personalized treatment in a shared decision-making model. The context of the model and the intervention, which uses a personalized, holistic, patient-centered approach that supports and facilitates agency enhancement within patients is described. The hypothesized mechanism of recovery is improved individual agency of the patient. Mixed methods were used to assess the proposed configuration. Illness severity measures were compared before engagement and 1-2 years after treatment onset. Results show improved functioning as well as improved symptoms, better quality of life and satisfaction with care. Individuals experienced significant functional improvement, with a large effect size. Symptoms and quality of life also improved significantly with large effect sizes. Reported satisfaction was high. Improvement in functioning was correlated with improvement in coping style but not age, number of visits, duration between timepoints or total number of traumatic exposures. Qualitative data also addressed the hypothesized mechanism of recovery. Youth identified their own engagement in care as an essential source of recovery and attributed improved agency as integral to overcoming life disruptions caused by mental illness. This realist evaluation is preliminary or pilot, and future work is needed to assess the hypothesized configuration more comprehensively and in different populations.

Identifiers

PMID41661809
PMCPMC12798563

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.