Evidence map›Paper›PMID 41661780›Full record

ArticlePLOS mental health2024

Age-at-migration, ethnicity and psychosis risk: Findings from the EU-GEI case-control study.

Humma Andleeb, Bettina Moltrecht, Charlotte Gayer-Anderson, Celso Arango, Manuel Arrojo, Giuseppe D'Andrea, Miquel Bernardo, Christina Marta Del-Ben, Lieuwe de Haan, Laura Ferraro and 17 more

Abstract read
In one paragraph

Article in PLOS mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Humma AndleebPsyLife Group, Division of Psychiatry, UCL, London, United Kingdom.ORCID https://orcid.org/0000-0001-5410-7725
Bettina MoltrechtEvidence-Based Practice Unit, Anna Freud Centre and UCL, London, United Kingdom.ORCID https://orcid.org/0000-0002-1838-428X
Charlotte Gayer-AndersonDepartment of Health Service and Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0003-1636-889X
Celso ArangoDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon, Madrid, Spain.
Manuel ArrojoSchool of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Giuseppe D'AndreaUniversity of Montreal Hospital Research Centre (CRCHUM), Montréal, Québec, Canada.ORCID https://orcid.org/0000-0001-7014-645X
Miquel BernardoBarcelona Clinic Schizophrenia Unit, Hospital Clinic, Departament de Medicina, Institut de Neurociències (UBNeuro), Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), CIBERSAM, ISCIII, Universitat de Barcelona (UB), Barcelona, Spain.ORCID https://orcid.org/0000-0001-8748-6717
Christina Marta Del-BenNeuroscience and Behavior Departmente, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Lieuwe de HaanDepartment of Psychiatry, Early Psychosis Section, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
Laura FerraroDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Palermo, Italy.
Daniele La BarberaDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Palermo, Italy.
Erika La CasciaDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Palermo, Italy.
Pierre-Michel LlorcaCentre Hospitalier et Universitaire, Département de Psychiatrie, CNRS, Clermont Auvergne INP, Institut Pascal (UMR 6602), Université Clermont Auvergne, Clermont-Ferrand, France.
Paolo Rossi MenezesDepartment of Preventive Medicine, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-6330-3314
Diego QuattroneSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Julio SanjuánHospital Clínico Universitario de Valencia, Universidad de Valencia, Valencia, Spain.
Jean-Paul SeltenSchool for Mental Health and Neuroscience, University of Maastricht, Maastricht, The Netherlands.
Andrei SzökeUniv Paris Est Creteil, INSERM, IMRB, AP-HP, Hôpitaux Universitaires "H. Mondor", DMU IMPACT, Fondation Fondamental, Creteil, France.ORCID https://orcid.org/0000-0003-2973-7981
Ilaria TarriconeBologna Transcultural Psychosomatic Team (BoTPT), Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Els van der VenDepartment of Clinical, Developmental and Neuropsychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Eva VelthorstDepartment of Research, Community Mental Health Service GGZ Noord-Holland-Noord, Heerhugowaard, the Netherlands.ORCID https://orcid.org/0000-0002-9240-2909
Bart P F RuttenDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, the Netherlands.
Peter B JonesDepartment of Psychiatry, Cambridgeshire & Peterborough NHS Foundation Trust, University of Cambridge and CAMEO, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0002-0387-880X
Craig MorganESRC Centre for Society and Mental Health, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.
Hannah E JongsmaCentre for Transcultural Psychiatry "Veldzicht" Balkbrug, Balkbrug, the Netherlands.
Julian Edbrooke-ChildsClinical, Educational and Health Psychology, UCL, London, United Kingdom.ORCID https://orcid.org/0000-0003-0401-4058
James B KirkbridePsyLife Group, Division of Psychiatry, UCL, London, United Kingdom.ORCID https://orcid.org/0000-0003-3401-0824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have highlighted increased psychosis risk in migrant and minority ethnic populations. Migration before age 18 appears to increase risk, but further evidence is required. We investigated this issue in a European case-control study. We hypothesized that migration during two key socio-developmental periods, childhood and adolescence, would be most strongly associated with increased odds of psychosis, and that this would be more pronounced for racialised minorities. We used data from five countries in the EUropean network of national schizophrenia networks studying Gene-Environment Interactions [EU-GEI] study. We examined the association between migration in infancy (0-4 years), childhood (5-10 years), adolescence (11-17 years) or adulthood (18+ years) and first episode psychotic disorder. We fitted unadjusted and adjusted logistic regression models to estimate odds ratios [OR] and 95% confidence intervals [95%CI] for associations between age-at-migration and psychosis. In stratified models, we also examined whether these associations varied by ethnicity. The sample consisted of 937 cases and 1,195 controls. Migration at all ages, including infancy (OR: 2.03, 95%CI: 1.01-4.10), childhood (OR: 2.07, 95%CI: 1.04-4.14), adolescence (OR: 3.26, 95%CI: 1.89-5.63) and adulthood (OR: 1.71, 95%CI: 1.21-2.41), was associated with increased odds of psychosis compared with the white majority non-migrant group, after adjustment for all confounders except ethnoracial identity. After additional adjustment for ethnoracial identity, only migration during adolescence remained associated with psychosis (OR 1.94, 95%CI: 1.11-3.36). In stratified analyses, migration during adolescence was associated with increased odds of psychosis in Black (OR: 6.52, 95%CI: 3.00-14.20) and North African (OR: 16.43, 95%CI: 1.88-143.51) groups.Migration during adolescence increased psychosis risk, particularly in racially minoritised young people. This suggests that development of interventions for minoritised young migrants that alleviate stressors associated with migration and acculturation are warranted.

Identifiers

PMID41661780
PMCPMC12798472

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.