Evidence map›Paper›PMID 41661559›Full record

ArticleJournal of the International Society of Sports Nutrition2026

Intra-individual reliability of blood bicarbonate responses and gastrointestinal symptoms following sodium citrate supplementation.

Chris J McManus, Bernard X W Liew, Sally P W Waterworth, Henry C Chung

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Journal of the International Society of Sports Nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07737327 (The Acute Effects of Individually Timed Sodium Citrate Ingestion on Repeated Sprint Performance in Professional Female Soccer Players), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07737327 nanot yet recruitingnot on this map

The Acute Effects of Individually Timed Sodium Citrate Ingestion on Repeated Sprint Performance in Professional Female Soccer Players: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

TypeinterventionalSponsorHacettepe UniversityRan2026 to 2027Enrolled20ConditionsExercise-Induced Fatigue, Athletic Performance, SoccerArmsSodium Citrate Oral Product, Placebo
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Chris J McManusSchool of Sport, Rehabilitation and Exercise Sciences, University of Essex, Colchester, Essex, United Kingdom.ORCID 0000-0003-3871-3842
Bernard X W LiewSchool of Sport, Rehabilitation and Exercise Sciences, University of Essex, Colchester, Essex, United Kingdom.ORCID 0000-0002-7057-7548
Sally P W WaterworthSchool of Sport, Rehabilitation and Exercise Sciences, University of Essex, Colchester, Essex, United Kingdom.ORCID 0000-0002-9955-4497
Henry C ChungSchool of Sport, Rehabilitation and Exercise Sciences, University of Essex, Colchester, Essex, United Kingdom.ORCID 0000-0003-3285-2892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSodium citrate (SC) can elevate extracellular buffering capacity, yet the intra-individual reliability of its blood bicarbonate ([HCO₃

methodsTwelve healthy males (21 ± 1 yr) ingested a solution containing 0.5 g·kg

results[HCO₃

conclusionSC elicits a consistent group-level alkalosis, yet individual timing metrics are unreliable. Concentration-based indices are more stable for monitoring. Practically, a 2-3 h ingestion window maximizes the probability of achieving ≥+5 mmol·L

Indexed as

BicarbonatesCitratesDietary SupplementsGastrointestinal DiseasesGastrointestinal TractArea Under CurveHumansMaleReproducibility of ResultsSodium CitrateYoung AdultBicarbonatesCitratesSodium Citrateblood bicarbonateergogenic aidsextracellular bufferinggastrointestinal symptomsreliabilitySodium citrate

Identifiers

PMID41661559
PMCPMC12888348

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.