Presenteeism in working-age breast cancer survivors 1-5 years after surgery: relative contributions of treatment-related symptoms and modifiable factors.

Masahiro Manfuku, Ryota Imai, Satoko Yono, Hiroe Kanamori, Kazuhiro Sumiyoshi

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Article in Breast cancer (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Masahiro ManfukuDepartment of Rehabilitation, Breast Care Sensyu Clinic, Osaka, Japan. sunday_attinente@yahoo.co.jp.ORCID http://orcid.org/0000-0003-2537-7106

Ryota ImaiDepartment of Rehabilitation, Osaka Kawasaki Rehabilitation University, Osaka, Japan.

Satoko YonoDepartment of Rehabilitation, Breast Care Sensyu Clinic, Osaka, Japan.

Hiroe KanamoriDepartment of Breast Oncology, Breast Care Sensyu Clinic, Osaka, Japan.

Kazuhiro SumiyoshiDepartment of Breast Oncology, Breast Care Sensyu Clinic, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPresenteeism among working-age breast cancer survivors drives job loss and economic burden, but the extent to which it is attributable to treatment-related symptoms remains unclear. We examined determinants of presenteeism severity 1-5 years after surgery and preferences for support.

methodsIn this cross-sectional study, presenteeism was assessed with the Work Productivity and Activity Impairment questionnaire in 203 employed survivors (< 65 years) 1-5 years post-surgery. Presenteeism was modeled using hierarchical multiple linear regression with four blocks: (1) patient characteristics/treatment exposures; (2) work-related factors; (3) psychological symptoms and health literacy; and (4) physical function and cancer treatment-related symptoms. A modifiable-only sensitivity model with prespecified clinical cutoffs was also estimated.

resultsPresenteeism was present in 55.7% and severe in 27.1%. Model fit improved stepwise, with the largest incremental variance at Step 4. In the final model, higher presenteeism was independently associated with aromatase inhibitor-induced musculoskeletal symptoms, postmastectomy pain syndrome, greater cancer-related fatigue, reduced shoulder range of motion, and non-desk-based work (all p < 0.05). Over 70% preferred physiotherapy or pharmacotherapy.

conclusionPresenteeism in working-age survivors of breast cancer was strongly associated with modifiable treatment-related symptoms. Based on our findings, multidisciplinary, patient-centered interventions are recommended to support job retention and reintegration.

Indexed as

Breast NeoplasmsCancer SurvivorsMastectomyPresenteeismAdultCross-Sectional StudiesFemaleHumansMiddle AgedSurveys and QuestionnairesBreast cancer survivorsCancer treatment-related symptomsPresenteeismSupportive careWork impairment

Identifiers

PMID41661505

DOI10.3390/ijerph17082950

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