Hypercapnia at admission, regardless of acidosis, may worsen the outcome of hospitalised patients with chronic obstructive pulmonary disease exacerbations.

Giulia Sartori, Alberto Fantin, Filippo Sartori, Albert Gabarrús, Ernesto Crisafulli, Antoni Torres

Abstract read

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Article in Internal and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Giulia SartoriDepartment of Medicine, Respiratory Medicine Unit, University of Verona and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.ORCID http://orcid.org/0000-0003-1283-4718

Alberto FantinDepartment of Medicine, Respiratory Medicine Unit, University of Verona and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.ORCID http://orcid.org/0000-0002-5707-775X

Filippo SartoriDepartment of Medicine, Respiratory Medicine Unit, University of Verona and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

Albert GabarrúsDepartment of Pulmonology, Clinic Institute of Thorax (ICT), Hospital Clinic of Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona-Ciber de Enfermedades Respiratorias (CIBERES), Villarroel 170, 08036, Barcelona, Spain.

Ernesto CrisafulliDepartment of Medicine, Respiratory Medicine Unit, University of Verona and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.ORCID http://orcid.org/0000-0001-7298-7084

Antoni TorresDepartment of Pulmonology, Clinic Institute of Thorax (ICT), Hospital Clinic of Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona-Ciber de Enfermedades Respiratorias (CIBERES), Villarroel 170, 08036, Barcelona, Spain. atorres@recerca.clinic.cat.ORCID http://orcid.org/0000-0002-8643-2167

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with exacerbation of chronic obstructive pulmonary disease (ECOPD), the presence of respiratory acidosis is considered "a marker of severity", identifying the need for ventilation treatment. The evaluation of ECOPD patients with hypercapnia, even without acidosis, may provide information on patients not commonly defined as "at risk". We retrospectively assessed 407 hospitalised patients with ECOPD, divided into three groups at admission: patients with normocapnia (N = 176), hypercapnia (PaCO

Indexed as

AcidosisAcidosis, RespiratoryHypercapniaPulmonary Disease, Chronic ObstructiveAgedAged, 80 and overDisease ProgressionFemaleHospitalizationHumansMalePrognosisRetrospective StudiesAcidosisCOPD exacerbationsHospitalisationHypercapniaOutcomesPrognosis

Identifiers

PMID41661467

DOI10.1007/s11739-026-04279-0

PMCPMC13263262

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.