Evidence map›Paper›PMID 41661433›Full record

ArticleBulletin of experimental biology and medicine2025

Early Postnatal Stress as a Risk Factor for Cardiac Pathology in Systemic Inflammatory Conditions: An Experimental Study.

E E Pinaeva, E N Sazonova, D V Yakovenko, Yu B Malofey, V O Krechetova, A O Chernyavskiy, O G Pinaeva

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

E E PinaevaFar-East State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia. ekaterinabaglaevakhv@gmail.com.
E N SazonovaFar-East State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia.
D V YakovenkoFar-East State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia.
Yu B MalofeyFar-East State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia.
V O KrechetovaFar-East State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia.
A O ChernyavskiyFar-East State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia.
O G PinaevaFar-East State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The myocardial response was evaluated in adult male Wistar rats subjected to early postnatal stress (maternal separation) and subsequently administered a single intraperitoneal injection of LPS from E. coli O26:B6 (Sigma-Aldrich) at a dose of 2.5 mg/kg (MS + LPS group). Control animals were neither exposed to early postnatal stress nor treated with LPS, while the comparison group consisted of non-stressed animals that received LPS (LPS group). Both the LPS and MS + LPS groups exhibited an increased proportion of p53

Indexed as

InflammationMyocytes, CardiacStress, PsychologicalAnimalsAnimals, NewbornFemaleLipopolysaccharidesMaleMaternal DeprivationMyocardiumNitric Oxide Synthase Type IIIRatsRats, WistarRisk FactorsTroponin ITumor Suppressor Protein p53LipopolysaccharidesNitric Oxide Synthase Type IIINos3 protein, ratTroponin ITumor Suppressor Protein p53cardiomyocytesearly postnatal stresslipopolysaccharidesystemic inflammatory response

Identifiers

PMID41661433

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.