SynthesisPediatric surgery international2026
Optimal enteral feeding after surgery for necrotising enterocolitis: a systematic review.
Synthesis in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To review the evidence for enteral feed modification after surgery for Necrotising Enterocolitis (NEC) and determine the optimal feeding regime for these babies. A systematic review of the Scopus and PubMed databases was carried out. Papers reporting feed regimes in babies following surgery for NEC and reporting at least one clinical outcome were included. The ROBINS-I tool was utilised to evaluate the risk of bias. The search strategy returned 2772 records. After deduplication and screening against the inclusion/exclusion criteria, 11 studies were included in the review. Three studies reported the implementation of a standardised feeding regime; one led to earlier introduction of enteral feed, two found no increase in NEC recurrence and all three saw a reduction in liver dysfunction. There is a paucity of high quality evidence to guide specific post-operative feeding strategies in infants following surgery for NEC. However, limited available data suggest that achieving early enteral nutrition is not associated with worse short-term outcomes and may be associated with reduced parenteral nutrition dependence, improved growth, and lower feed-related complications. Large prospective and multicentre studies are needed to define optimal feeding composition, timing and advancement strategies to improve post-operative outcomes in this vulnerable neonatal population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.