Evidence map›Paper›PMID 41661325›Full record

ArticleSurgery today2026

Postoperative outcomes of pancreatoduodenectomy for pancreatic head malignancy in patients over 85 years of age: A safety evaluation using propensity score matching.

Shohei Yoshiya, Yo-Ichi Yamashita, Naotaka Inomata, Ippei Kawada, Sota Nakamura, Kazuhiro Tada, Yosuke Kuroda, Kentaro Iwaki, Kengo Fukuzawa, Tomoharu Yoshizumi

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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shohei YoshiyaDepartment of Surgery, Japanese Red Cross Oita Hospital, 3-2-37 Chitomachi, Oita, 870-0033, Japan. shoheiyoshiya@gmail.com.ORCID http://orcid.org/0000-0003-4642-5058
Yo-Ichi YamashitaDepartment of Surgery, Japanese Red Cross Oita Hospital, 3-2-37 Chitomachi, Oita, 870-0033, Japan.
Naotaka InomataDepartment of Surgery, Japanese Red Cross Oita Hospital, 3-2-37 Chitomachi, Oita, 870-0033, Japan.
Ippei KawadaDepartment of Surgery, Japanese Red Cross Oita Hospital, 3-2-37 Chitomachi, Oita, 870-0033, Japan.
Sota NakamuraDepartment of Surgery, Japanese Red Cross Oita Hospital, 3-2-37 Chitomachi, Oita, 870-0033, Japan.
Kazuhiro TadaDepartment of Surgery, Japanese Red Cross Oita Hospital, 3-2-37 Chitomachi, Oita, 870-0033, Japan.
Yosuke KurodaDepartment of Surgery, Japanese Red Cross Oita Hospital, 3-2-37 Chitomachi, Oita, 870-0033, Japan.
Kentaro IwakiDepartment of Surgery, Japanese Red Cross Oita Hospital, 3-2-37 Chitomachi, Oita, 870-0033, Japan.
Kengo FukuzawaDepartment of Surgery, Japanese Red Cross Oita Hospital, 3-2-37 Chitomachi, Oita, 870-0033, Japan.
Tomoharu YoshizumiDepartment of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.

Funding

Japan Society for the Promotion of Science KAKENHI Grant Number JP-23K08214
6 · The paper itself

Abstract

introductionAs the global population ages, older patients undergo pancreatoduodenectomy (PD). This study aimed to evaluate the safety and postoperative outcomes of PD in patients > 85 years of age.

methodsWe reviewed 200 consecutive PDs and compared the postoperative outcomes in patients aged ≥ 85 years using propensity score matching (PSM).

resultsAfter PSM, no differences in the clinical characteristics were observed between the two cohorts (n = 16 each). Those aged ≥ 85 years had a significantly lower induction rate of adjuvant chemotherapy (p < 0.0001) and a higher rate of best supportive care selection at recurrence (BSC) (p = 0.033) than those aged < 85 years. There was no significant difference in the rate of non-cancer-related deaths (p = 0.18). Although there were no significant differences in the -free survival rates (p = 0.89), the overall survival rate of those ≥ 85 years was significantly worse (p = 0.023). The risk factors for death after surgery were tumor-related factors and BSC (p = 0.0012). An age ≥ 85 years was not a risk factor for major postoperative complications or death after surgery.

conclusionsPD can be safely performed in patients aged ≥ 85 years without increasing postoperative complications and recurrences in the cases with appropriate patient selection.

Indexed as

Pancreatic NeoplasmsPancreaticoduodenectomyPropensity ScoreAged, 80 and overAge FactorsChemotherapy, AdjuvantFemaleHumansMalePostoperative ComplicationsRisk FactorsSurvival RateTreatment OutcomeElderlyMalignancyPancreaticPancreatoduodenectomySafety

Identifiers

PMID41661325

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.