Evidence map›Paper›PMID 41661320›Full record

ArticleParasitology research2026

Impact of olfactory sensitivity preferences on midgut pathophysiology of Aedes mosquitoes towards different sugar variants.

Ranjitha Sambanthan, Nur Faeza Abu Kassim, Sara Abdelrahman Abuelmaali, Wan Maryam Wan Ahmad Kamil, Sumiyyah Sabar, Kamarul Zaman Zarkasi, Wan Rosli Wan Ishak, Cameron E Webb

Abstract read
In one paragraph

Article in Parasitology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ranjitha Sambanthan129 Medical Entomology Laboratory, School of Biological Sciences, Universiti Sains Malaysia, Minden, Penang, 11800, Malaysia.
Nur Faeza Abu Kassim129 Medical Entomology Laboratory, School of Biological Sciences, Universiti Sains Malaysia, Minden, Penang, 11800, Malaysia. nurfaeza@usm.my.
Sara Abdelrahman Abuelmaali129 Medical Entomology Laboratory, School of Biological Sciences, Universiti Sains Malaysia, Minden, Penang, 11800, Malaysia.
Wan Maryam Wan Ahmad KamilSchool of Physics, Universiti Sains Malaysia, Minden, Penang, 11800, Malaysia.
Sumiyyah SabarChemical Sciences Programme, School of Distance Education (SDE), Universiti Sains Malaysia, Minden, Penang, 11800, Malaysia.
Kamarul Zaman ZarkasiSchool of Health Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, 16150, Malaysia.
Wan Rosli Wan IshakMedical Entomology, NSW Health Pathology, Westmead Hospital, Westmead, NSW, 2145, Australia.
Cameron E WebbMedical Entomology, NSW Health Pathology, Westmead Hospital, Westmead, NSW, 2145, Australia.

Funding

Fundamental Research Grant Scheme (FRGS) FRGS/1/2022/STG03/USM/02/8
6 · The paper itself

Abstract

The effective control of Aedes mosquitoes is increasingly challenging due to the presence of insecticide resistance in mosquitoes. Hence, attractive toxic sugar baits (ATSBs) can be used as an alternative strategy to insecticides. The introduction of suitable attractants into baits is crucial, as it determines the number of mosquitoes attracted to them. This study involved the preparation of ATSBs as a medium for liquid bait carriers aimed at developing mosquito baiting tools. Aedes aegypti and Aedes albopictus were tested for non-choice and choice assays against various ATSBs (mango, Chrysanthemum, and their mix). In addition, olfactory preference index for mosquitoes was calculated using preference index formula followed by independent t- test to determine the significant differences, (p < 0.05) between ATSBs various choices. Furthermore, the midgut tissue of the mosquitoes was observed by using histology method. The wild and lab strain Ae. aegypti showed a significant attractancy towards mango ATSBs with a value of (p = 0.004) and (p = 0.04) respectively. Mango attractant is the most preferred by both Aedes sp. However, the mix ATSBs is secondarily preferred while Chrysanthemum is the least preferred ATSBs. The histology results showed that the midgut of mosquitoes that feed on the treated ATSBs exhibit alteration and degeneration. In the context of integrated pest management, the application of ATSBs in mosquito control may diminish the reliance on chemical pesticides, as natural substances include inherent volatile emissions that attract or repel insects. Consequently, the continuous release of the natural attractant odour may play a significant role in the attractive toxic sugar bait, acting as both an attractant and a lethal mechanism to combat disease transmitted by mosquitoes in the future.

Indexed as

AedesMosquito ControlSugarsAnimalsFemaleGastrointestinal TractInsecticidesInsecticidesSugarsAedesBaitsHistologyMidgutOlfaction

Identifiers

PMID41661320
PMCPMC12891037

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.