Evidence map›Paper›PMID 41661307›Full record

SynthesisDysphagia2026

Effectiveness of Combined Rehabilitation Approaches in Post-Stroke Dysphagia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Ibrahim M Alayaseh, Ponnusamy Subramaniam, Thanzeem Razak, Yaser S Natour, Marissa A Barrera, Shobha Sharma

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Dysphagia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ibrahim M AlayasehCentre for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Ponnusamy SubramaniamCentre for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Thanzeem RazakHamad Medical Corporation, Doha, Qatar.
Yaser S NatourThe University of Jordan, Amman, Jordan.
Marissa A BarreraYeshiva University, New York, USA.
Shobha SharmaCentre for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia. shobha.sharma@ukm.edu.my.ORCID http://orcid.org/0000-0002-3396-7053

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review and meta-analysis critically examine the efficacy of combined rehabilitation strategies, specifically the integration of swallowing exercises, neuromuscular electrical stimulation (NMES), and neuromuscular taping (NMT), in the management of post-stroke dysphagia. Four databases (Scopus, ScienceDirect, Cochrane Library, and PubMed) were searched for studies published from January 1990 to December 2024. Reference lists from relevant articles were also reviewed. A total of 372 studies were identified. After screening titles, abstracts, and full texts, 18 studies met the inclusion criteria. POPULATION: Adults (≥ 18 years) with post-stroke dysphagia in the acute or subacute phases.

interventionSwallowing exercises, NMES, NMT, or a combination. COMPARATOR: Control groups with single interventions, usual care, or traditional therapies. OUTCOMES: Primary outcomes included swallowing function, aspiration pneumonia reduction, and quality of life. Secondary outcomes examined the timing, intensity, and type of interventions. Data were extracted using a standardized form in Microsoft Excel, focusing on study characteristics, participant demographics, intervention details, and outcome measurements. This systematic review supports the effectiveness of combined intervention approaches for post-stroke dysphagia. The meta-analysis revealed a significant improvement in swallowing function, with a pooled effect size of -1.27, indicating reduced Penetration-Aspiration Scale (PAS) scores. The random-effects pooled effect size was - 1.49 (95% CI: -1.92 to -1.06). Substantial heterogeneity (I² = 67.37%) was observed, likely attributable to differences in study methodologies, intervention protocols, and participant characteristics. The findings support the efficacy of combined rehabilitation strategies for post-stroke dysphagia. Certain combined interventions, particularly those incorporating NMES, show promise of effectiveness. However, the effectiveness of other modalities, such as kinesiology taping and chin tuck against resistance, remains less consistent and requires further investigation. REGISTRATION NUMBER: PROSPERO Registration ID: CRD42025645917.

Indexed as

Deglutition DisordersElectric Stimulation TherapyExercise TherapyStrokeStroke RehabilitationCombined Modality TherapyHumansQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeChin tuck against resistanceCombined rehabilitationDysphagiaExpiratory muscle strength trainingKinesiology tapingNeuromuscular electrical stimulationNeuromuscular tapingPost-strokeTraditional swallowing therapy

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.