ArticleJACC. Case reports2026
Malignant Hypertension and Torsades De Pointes as Initial Presentations of Primary Aldosteronism.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPrimary aldosteronism (PA) is a common yet underdiagnosed cause of secondary hypertension, particularly in young patients presenting with severe disease. CASE SUMMARY: A 31-year-old woman presented with malignant hypertension (264/144 mm Hg), severe hypokalemia (K DISCUSSION: This case report highlights the interference of common medications in PA diagnosis, delineates the complete pathophysiological cascade from aldosterone excess to life-threatening arrhythmia, and reveals the dynamic nature of PA-associated adrenal nodules. TAKE-HOME MESSAGES: Clinicians must be vigilant about the confounding effects of common antihypertensive agents on ARR interpretation and should consider adrenal imaging as part of the dynamic management of PA. Adrenal venous sampling remains paramount for surgical planning.
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