Evidence map›Paper›PMID 41661106›Full record

ReviewInfection and immunity2026

Post-TB lung disease: pathogenesis, host-directed therapies, and the C3HeB/FeJ model for pre-clinical advances.

Boatema Ofori-Anyinam, Brian Nyiro, Padmini Salgame

Abstract readReview
In one paragraph

Review in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Boatema Ofori-AnyinamDepartment of Medicine, Center for Emerging Pathogens, Rutgers New Jersey Medical School, Newark, New Jersey, USA.ORCID 0000-0002-8981-8188
Brian NyiroDepartment of Medicine, Center for Emerging Pathogens, Rutgers New Jersey Medical School, Newark, New Jersey, USA.ORCID 0000-0001-7131-8137
Padmini SalgameDepartment of Medicine, Center for Emerging Pathogens, Rutgers New Jersey Medical School, Newark, New Jersey, USA.ORCID 0000-0003-2245-3767

Funding

National Institute of Allergy and Infectious Diseases AI177788
6 · The paper itself

Abstract

More than half of the people with microbiologically cured tuberculosis (TB) present with post-TB lung disease (PTLD). PTLD compromises long-term respiratory health and adds to the global burden of chronic lung diseases. Despite its prevalence, the mechanisms driving tissue damage in TB are not well understood. In this review, we discuss the global burden of PTLD, evaluate host-directed therapies as promising interventions, and highlight the C3HeB/FeJ mouse model as a powerful tool for advancing pre-clinical PTLD research.

Indexed as

Lung DiseasesTuberculosis, PulmonaryAnimalsDisease Models, AnimalHost-Directed TherapyHumansMiceC3HeB/FeJhost-directed therapyimmunopathogenesispost-TB lung diseasePTLDtuberculosis

Identifiers

PMID41661106
PMCPMC12974129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.