Evidence map›Paper›PMID 41660940›Full record

ArticleJournal of Alzheimer's disease : JAD2026

Educational attainment is associated with reduced functional decline in Puerto Ricans with elevated pTau181.

Daniel A Dorfsman, Dingtian Cai, Kara L Hamilton-Nelson, Larry D Adams, Pedro R Mena, Vanessa C Rodriguez, Jose Javier Sanchez, Glenies S Valladares, Mariangelie Lopez, Patrice L Whitehead and 25 more

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Daniel A DorfsmanJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Dingtian CaiJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Kara L Hamilton-NelsonJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Larry D AdamsJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Pedro R MenaJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Vanessa C RodriguezJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Jose Javier SanchezJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Glenies S ValladaresJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Mariangelie LopezJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Patrice L WhiteheadJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Michael B ProughJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Patricia ManriqueJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Anisley MartinezJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Sabrina M MasJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Carolina ScaramuttiDepartment of Informatics and Health Data Science, University of Miami Miller School of Medicine, Miami, FL, USA.
Heriberto AcostaClinica de la Memoria, San Juan, PR, USA.
Concepcion Silva-VergaraUniversidad Central del Caribe, Bayamón, PR, USA.
Katalina McInerneyDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
Anthony J GriswoldJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Briseida E Feliciano-AstacioUniversidad Central del Caribe, Bayamón, PR, USA.
Michael L CuccaroJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Brian W KunkleJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Christiane ReitzGertrude H. Sergievsky Center, Taub Institute for Research on the Aging Brain, Department of Neurology, Psychiatry, and Epidemiology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Giuseppe TostoGertrude H. Sergievsky Center, Taub Institute for Research on the Aging Brain, Department of Neurology, Psychiatry, and Epidemiology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
William S BushCleveland Institute for Computational Biology, Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Jonathan L HainesCleveland Institute for Computational Biology, Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Joshua O AkinyemiInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Rufus O AkinyemiInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Adesola OgunniyiInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Goldie S ByrdDepartment of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Jeffery M VanceJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Katrina CelisJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Azizi SeixasDepartment of Informatics and Health Data Science, University of Miami Miller School of Medicine, Miami, FL, USA.
Margaret A Pericak-VanceJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
Farid RajabliJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)U19AG074865 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GOLDIE S. BYRD, William S Bush · 2022 to 2026
$55.3M
Genomic Characterization of Alzheimer Disease Risk in Admixed Populations with Native American and Southern European Genetic AncestryR01AG070864 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Margaret A. Pericak-Vance, FARID RAJABLI · 2021 to 2026
$12.1M
NIA NIH HHS R01 AG070864NIA NIH HHS U19 AG074865
6 · The paper itself

Abstract

BackgroundEducation promotes cognitive reserve (CR), potentially buffering Alzheimer's disease pathology (ADP). However, the education-CR relationship may differ by population and genetic background.ObjectiveTo examine education,

Indexed as

Alzheimer DiseaseCognitive ReserveEducational Statustau ProteinsAgedAged, 80 and overApolipoprotein E4BiomarkersFemaleHumansMalePuerto RicoApolipoprotein E4Biomarkerstau ProteinsAlzheimer's diseaseAPOEcognitive reserveeducationplasma biomarkers

Identifiers

PMID41660940
PMCPMC12982544

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.