ArticleMicrobiology spectrum2026
Demographic and clinical correlates of discordant QuantiFERON TB Gold tuberculosis screening results in a low-incidence setting.
Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Interferon-γ release assays (IGRAs), such as the QuantiFERON-TB Gold Plus (QFTTB), are commonly used to detect past exposure to IMPORTANCE: Reliable interpretation of interferon-γ release assays (IGRAs) is critical for the diagnosis and management of latent tuberculosis infection (LTBI). However, variability in test performance during serial or confirmatory testing complicates clinical decision-making and may result in unnecessary treatment. Our study demonstrates that demographic factors, clinical comorbidities, and testing intervals contribute to discordant QuantiFERON-TB Gold Plus results. These findings underscore the need to integrate epidemiologic risk, pre-test probability of
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