Evidence map›Paper›PMID 41660847›Full record

ArticleMicrobiology spectrum2026

A novel parvovirus circulating in canine populations and sporadically detected in human oropharyngeal samples.

Xiang Lu, Ning Kong, Chunmei Wang, Juan Lu, Wang Li, Hongfeng Yang, Xiaoxiao Lu, Zheyuan Zhang, Yue Chen, Shiyin Huang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiang Lu *Institute of Critical Care Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.ORCID 0000-0003-2987-9664
Ning Kong *Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.ORCID 0000-0001-7264-9069
Chunmei Wang *Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.ORCID 0000-0001-9860-6876
Juan LuInstitute of Critical Care Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.
Wang LiInstitute of Critical Care Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.
Hongfeng YangInstitute of Critical Care Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.ORCID 0000-0001-9624-6109
Xiaoxiao LuShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Zheyuan ZhangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Yue ChenInstitute of Critical Care Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.
Shiyin HuangInstitute of Critical Care Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.
Chenglin ZhouClinical Laboratory Center, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China.
Yu ZhangDepartment of Preventive Dentistry, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0003-0401-3768
Wen ZhangInstitute of Critical Care Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, China.ORCID 0000-0002-9352-6153
Tongling ShanShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.ORCID 0000-0002-5329-6349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most human pathogens, while originating from animals, have crossed species barriers to infect humans, often leading to outbreaks of new infectious diseases. Despite significant efforts, the mechanisms, timing, and locations of these emerging diseases remain largely uncertain. Here, using a viral metagenomic approach, we discovered a novel canine-associated parvovirus in human oropharyngeal secretions. Molecular screening revealed the presence of this parvovirus in different canine tissues, including 24 of 108 pharyngeal lymph node samples. Further molecular investigation showed that the virus was detected in the oropharyngeal secretions of pet dogs and in human samples that were not linked to these animals. This parvovirus was therefore named human-canine associated parvovirus 1 (HCAPV-1). Nine complete genomes of HCAPV-1 were acquired through next-generation sequencing, combining Sanger sequencing. Genomic and phylogenetic analyses indicate that these nine strains of HCAPV-1 belong to the genus

Indexed as

Dog DiseasesOropharynxParvoviridae InfectionsParvovirusParvovirus, CanineAnimalsCapsid ProteinsDogsGenome, ViralHigh-Throughput Nucleotide SequencingHumansMetagenomicsPhylogenyRecombination, GeneticCapsid Proteinscaninehumanparvovirusrecombination

Identifiers

PMID41660847
PMCPMC12955472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.