Evidence map›Paper›PMID 41660710›Full record

ReviewPharmacotherapy2026

Considerations for Menstrual Suppression in Patients With Hematologic Malignancies.

Sahaana Veeravalli, Allison Schepers, Lydia L Benitez, Martina S Fraga

Abstract readReview
In one paragraph

Review in Pharmacotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Women's Health in Oncology.Pharmacotherapy · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sahaana VeeravalliDepartment of Pharmacy, University of Michigan Health, Ann Arbor, Michigan, USA.ORCID 0009-0004-0621-1957
Allison SchepersDepartment of Pharmacy, University of Michigan Health, Ann Arbor, Michigan, USA.ORCID 0000-0002-2034-8528
Lydia L BenitezDepartment of Pharmacy, University of Michigan Health, Ann Arbor, Michigan, USA.ORCID 0000-0001-6828-8053
Martina S FragaDepartment of Pharmacy, University of Michigan Health, Ann Arbor, Michigan, USA.ORCID 0009-0003-2769-3951

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients who menstruate during treatment for hematologic malignancies have a higher risk of heavy vaginal bleeding due to thrombocytopenia caused by malignancy and myelosuppressive chemotherapy. Heavy menstrual bleeding is associated with significant morbidity in this patient population, and menstrual suppression is a standard of supportive care. Options for prophylactic menstrual suppression include gonadotropin-releasing hormone agonists, progestin-only therapy, and combined hormonal contraception. Various factors impact the choice of menstrual suppression agent, including efficacy, presence of emergent acute uterine bleeding, desire for contraception, and presence of thrombotic risk factors. The purpose of this review is to discuss the nuances of available menstrual suppression agents in patients with hematologic malignancies and develop a methodical approach to consider patient-specific factors that impact agent selection.

Indexed as

Hematologic NeoplasmsMenorrhagiaMenstruationAntineoplastic AgentsFemaleGonadotropin-Releasing HormoneHumansProgestinsAntineoplastic AgentsGonadotropin-Releasing HormoneProgestinshematologicmalignancymenstrual suppressionmenstruationprophylaxis

Identifiers

PMID41660710
PMCPMC12884572

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.