Evidence map›Paper›PMID 41660688›Full record

ArticleACS applied materials & interfaces2026

Vibration or Stretch? Distinct Mechanoelectrical Signatures Govern Osteogenic Programming in PVDF.

Sylvie Ribeiro, Clarisse Ribeiro, Nélson Castro, Vitor Correia, Igor Irastorza, Unai Silván, Senentxu Lanceros-Mendez

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sylvie RibeiroCF-UM-UP - Physics Centre of Minho and Porto Universities and LaPMET - Laboratory of Physics for Materials and Emergent Technologies, University of Minho, Braga 4710-057, Portugal.ORCID 0000-0002-7175-6273
Clarisse RibeiroCF-UM-UP - Physics Centre of Minho and Porto Universities and LaPMET - Laboratory of Physics for Materials and Emergent Technologies, University of Minho, Braga 4710-057, Portugal.ORCID 0000-0002-9120-4847
Nélson CastroAlgoritmi Research Centre, University of Minho, Campus de Azurém, Guimarães 4800-058, Portugal.ORCID 0000-0003-0648-2285
Vitor CorreiaSYSTEC- Research Center for Systems and Technologies- University of Porto (FEUP), Porto 4200-465, Portugal.ORCID 0000-0001-8318-085X
Igor IrastorzaCell Biology and Histology Department, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Unai SilvánBCMaterials, Basque Centre for Materials, Applications and Nanostructures, UPV/EHU Science Park, Leioa 48940, Spain.
Senentxu Lanceros-MendezCF-UM-UP - Physics Centre of Minho and Porto Universities and LaPMET - Laboratory of Physics for Materials and Emergent Technologies, University of Minho, Braga 4710-057, Portugal.ORCID 0000-0001-6791-7620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A promising method for directing cell behavior and tissue regeneration is the use of smart materials that can transform physical inputs into bioelectrical signals. In this study, the mechanoelectrical control of preosteoblast activity was investigated using a piezoelectric smart biointerface based on positively poled poly(vinylidene fluoride) (PVDF). Distinct mechanical regimes, including vibrational and cyclic stretching, were applied through customized bioreactors, enabling controlled mechanoelectrical inputs ranging from 63 to 227 μVpp mm

Indexed as

OsteogenesisPolyvinylsAlkaline PhosphataseAnimalsCell DifferentiationCell LineCell ProliferationFluorocarbon PolymersMiceOsteoblastsTissue EngineeringVibrationAlkaline PhosphataseFluorocarbon Polymerspolyvinylidene fluoridePolyvinylsbone tissue engineeringcalcium signalingcyclic stretchingmechanoelectrical stimulationosteogenic differentiationpiezoelectric scaffoldsvibration bioreactor

Identifiers

PMID41660688
PMCPMC12926946

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.