ArticleOpen forum infectious diseases2026
Bone and Joint Infections in Tropical Settings: High Prevalence of Gram-Negative Bacilli and Implications for Empirical Therapy.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Bone and joint infections (BJIs) are increasingly reported worldwide, but data on their epidemiology remain limited in tropical settings. We aimed to characterize the causative agents of BJIs and their resistance patterns, in order to inform empirical antibiotic in our tropical setting. Methods: This 6-year retrospective study included all adults with a first microbiologically confirmed episode of BJI between January 2019 and December 2024 at the Guadeloupe University Hospital, a tertiary care center in the Caribbean. Results: A total of 312 patients with BJI were included. Among the 449 isolates recovered, Gram-negative bacilli (GNB) were predominant (41%), including AmpC β-lactamase-producing Enterobacterales (13%, 59/449) and Conclusions: Our findings highlight the prominent role of GNBs in tropical BJI and support the implementation of local surveillance systems to guide empirical treatment strategies.
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