ArticleJRSM cardiovascular disease
Is left ventricular relative wall thickness a predictor of 5-year mortality in patients with acute decompensated heart failure?
Article in JRSM cardiovascular disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Heart failure (HF) is a significant global health problem that continues to increase in prevalence, morbidity, and mortality, particularly in aging populations. Relative wall thickness (RWT), an echocardiographic parameter reflecting geometric remodeling of the heart, is easily measurable and may possess prognostic value. This study aimed to evaluate the predictive power of RWT for 5-year mortality in patients with HF. Methods: In this retrospective observational analysis, a total of 232 individuals diagnosed with acute decompensated heart failure were enrolled. RWT values were calculated using echocardiographic measurements. In this single retrospective cohort, participants were stratified into two subgroups based on their 5-year survival status. Demographic, clinical, laboratory, and echocardiographic parameters were compared between these subgroups. Results: After 5 years of follow-up, 133 patients had died. Patients in the mortality group were significantly older (p = 0.001). The mortality cohort demonstrated a higher prevalence of chronic renal failure, atrial fibrillation, and mitral regurgitation compared with survivors. Echocardiographically, elevated systolic pulmonary artery pressure (sPAP) was associated with mortality (p = 0.009). However, regression analysis did not find sPAP to be statistically significant [95% confidence interval (CI), hazard ratio: 1.047 (0.818-1.340), p:0.7)]. RWT values did not show a significant difference between the groups (0.39 ± 0.13 compared to 0.37 ± 0.06; p = 0.225). Area under the curve for RWT was 0.50 (95% CI: 0.43-0.57), indicating poor predictive power. Kaplan-Meier analysis showed no significant difference in survival between RWT groups (log-Rank:0.984, p: 0.32). Conclusion: RWT has limited ability to predict 5-year mortality among patients with advanced stages of HF. Age emerged as the strongest independent predictor. RWT should be evaluated in conjunction with multiple clinical and laboratory parameters rather than in isolation when managing HF.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.