Evidence map›Paper›PMID 41660522›Full record

ArticleJournal of lipid and atherosclerosis2026

Hypertriglyceridemia in Type 2 Diabetes Is Associated With T Regulatory Cell Dysfunction.

Karthik Raj, Seema Garg, Mohit Mehndiratta, S V Madhu, Rajarshi Kar, Edelbert Anthonio Almeida

Abstract read
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In one paragraph

Article in Journal of lipid and atherosclerosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karthik RajDepartment of Biochemistry, University College of Medical Sciences and GTB Hospital, Delhi, India.ORCID https://orcid.org/0009-0001-1483-6306
Seema GargDepartment of Biochemistry, University College of Medical Sciences and GTB Hospital, Delhi, India.ORCID https://orcid.org/0000-0003-0044-5977
Mohit MehndirattaDepartment of Biochemistry, University College of Medical Sciences and GTB Hospital, Delhi, India.ORCID https://orcid.org/0000-0002-0822-6544
S V MadhuDepartment of Endocrinology, University College of Medical Sciences and GTB Hospital, Delhi, India.ORCID https://orcid.org/0000-0003-0018-5984
Rajarshi KarDepartment of Biochemistry, University College of Medical Sciences and GTB Hospital, Delhi, India.ORCID https://orcid.org/0000-0003-4509-2079
Edelbert Anthonio AlmeidaDepartment of Biochemistry, University College of Medical Sciences and GTB Hospital, Delhi, India.ORCID https://orcid.org/0000-0001-8301-7964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Hypertriglyceridemia (HTG), often but not always coexists with type 2 diabetes mellitus (T2DM). Both independently increase the risk of vascular complications, with inflammation serving as the underlying pathology. T-regulatory (Treg) cells, identified as CD4+CD25+forkheadbox-P3(FoxP3)+ cells, mitigate inflammation through secretion of interleukin(IL) 10. We investigated markers of Treg cell function in patients of T2DM with and without HTG. Methods: Patients with T2DM were divided into 2 groups: T2DM with normal triglyceride (TG) levels (n=30), designated as (DNT) and T2DM with HTG (n=30) designated as (DHTg). Expression of the Results: Conclusion: Reduced expression of

Indexed as

Forkhead box P3 proteinHypertriglyceridemiaIL-10Regulatory T-cellsType 2 diabetes mellitus

Identifiers

PMID41660522
PMCPMC12875080

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.