Evidence map›Paper›PMID 41660435›Full record

ArticleJournal of thoracic disease2026

Promotion of lung cancer growth via glutamate ionotropic receptor N-methyl-D-aspartate-type subunit 2D (

Yunluo Lv, Xinyi Bu, Zhongxiang Du, Yuan Zhang, Yanna Si, Hongwei Shi, Liu Han, Hongguang Bao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yunluo Lv *Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Xinyi Bu *Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Zhongxiang Du *Department of Clinical Laboratory, The People's Hospital of Danyang, Affiliated Danyang Hospital of Nantong University, Danyang, China.
Yuan ZhangDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Yanna SiDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Hongwei ShiDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Liu HanDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Hongguang BaoDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: N-methyl-D-aspartate receptors (NMDARs) are known to contribute to neurological and neurodegenerative diseases. Meanwhile, glutamate ionotropic receptor N-methyl-D-aspartate-type subunit 2D ( Methods: Through the use of quantitative reverse-transcription polymerase chain reaction (qRT-PCR), Results: In this study, we demonstrated that lung adenocarcinoma and related cancer cell lines had significantly high levels of Conclusions: This study is the first to identify the involvement of

Indexed as

esketamineGlutamate ionotropic receptor N-methyl-D-aspartate-type subunit 2D (GRIN2D)lung adenocarcinoma (LUAD)LY294002PI3K/mTOR signaling pathway

Identifiers

PMID41660435
PMCPMC12881852

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.