Evidence map›Paper›PMID 41660425›Full record

Observational studyFrontiers in cellular and infection microbiology2026

Clinical characteristics and prognostic impact of streptococcal colonization in critically ill patients with severe pneumonia.

Hang Ni, Jiaqi Zhu, Yanfang Chen, Ye Zheng, Benjia Chen, Cuicui Dong, Sheng Zhang, Yinghe Xu, Yongpo Jiang

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hang Ni *Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Shaoxing University, Taizhou, China.
Jiaqi Zhu *Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Shaoxing University, Taizhou, China.
Yanfang Chen *Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Shaoxing University, Taizhou, China.
Ye ZhengDepartment of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Shaoxing University, Taizhou, China.
Benjia ChenDepartment of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Shaoxing University, Taizhou, China.
Cuicui DongDepartment of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Shaoxing University, Taizhou, China.
Sheng ZhangDepartment of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Shaoxing University, Taizhou, China.
Yinghe XuDepartment of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Shaoxing University, Taizhou, China.
Yongpo JiangDepartment of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Shaoxing University, Taizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Method: We conducted a multicenter, retrospective, observational cohort study of critically ill pneumonia patients admitted to 12 intensive care units (ICUs) between January 2019 and December 2023 who underwent metagenomic next-generation sequencing (mNGS). Patients were stratified into Results: A total of 1,897 patients were enrolled in this study. Among them, 21 patients under 18 years of age, 139 patients lost to follow-up within 28 days, and 4 patients with confirmed streptococcal infection were excluded. Finally, 1,733 patients met the inclusion criteria. The cohort had a mean age of 65 years, with the majority being males (1,213/1,733, 70%). Among these, 148 (8.5%) were classified as Conclusion: Our findings suggest a potential role for

Indexed as

Streptococcal InfectionsStreptococcusAgedBronchoalveolar Lavage FluidCritical IllnessFemaleHumansIntensive Care UnitsMaleMiddle AgedPrognosisRetrospective Studiescolonizationmetagenomic sequencingpulmonary microbiomesevere pneumoniaStreptococcus

Identifiers

PMID41660425
PMCPMC12872922

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.