Evidence map›Paper›PMID 41660371›Full record

ArticleBrain, behavior, & immunity - health2026

Macrostructural, microstructural, and cellular effects of neuroinflammation on the mouse brain.

Yash Patel, Anita Woo, Sammy Shun Wai Shi, Eric Kim, Jean Shin, Yohan Yee, Jason P Lerch, Brian J Nieman, Tomas Paus, Zdenka Pausova

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain, behavior, & immunity - health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yash PatelCentre Hospitalier Universitaire Sainte-Justine, University of Montreal, QC, Canada.
Anita WooThe Hospital for Sick Children, Translational Medicine Program, Toronto, ON, Canada.
Sammy Shun Wai ShiThe Hospital for Sick Children, Translational Medicine Program, Toronto, ON, Canada.
Eric KimCentre Hospitalier Universitaire Sainte-Justine, University of Montreal, QC, Canada.
Jean ShinCentre Hospitalier Universitaire Sainte-Justine, University of Montreal, QC, Canada.
Yohan YeeThe Hospital for Sick Children, Translational Medicine Program, Toronto, ON, Canada.
Jason P LerchDepartment of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Brian J NiemanThe Hospital for Sick Children, Translational Medicine Program, Toronto, ON, Canada.
Tomas PausCentre Hospitalier Universitaire Sainte-Justine, University of Montreal, QC, Canada.
Zdenka PausovaCentre Hospitalier Universitaire Sainte-Justine, University of Montreal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation is increasingly implicated in post-infectious brain atrophy and cognitive impairment, as well as the etiology of neurodegenerative and psychiatric disorders. Here, we employed an established mouse model of neuroinflammation (systemic lipopolysaccharide [LPS]) and studied its macrostructural, microstructural, and cellular effects on the mouse brain. We combined whole-brain two-photon microscopy, multiparametric magnetic resonance imaging, and

Indexed as

BioinformaticsCellular component of synapseIn silico transcriptomicsLayer 4,5 excitatory neuronmultimodal magnetic resonance imaging of the brainNeuroinflammationPVALB inhibitory neuronTwo-photon imaging of microglia

Identifiers

PMID41660371
PMCPMC12873735

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.