ArticleSurgical neurology international2026
Cryptococcal dumbbell inflammatory pseudotumor mimicking skull histiocytic sarcoma in immunocompetent patient.
Article in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Case Description: A 34-year-old immunocompetent male presented with a painless, progressive left parieto-occipital scalp swelling over 3 weeks. Imaging revealed a well-defined, dumbbell-shaped cystic mass beneath the scalp, causing lytic skull erosion and limited intracranial extension, suggestive of atypical meningioma or skull-based sarcoma. Surgical excision was performed, showing dural infiltration without leptomeningeal spread. Histopathology, the mass revealed granulomatous inflammation with abundant CD68+ histiocytes, mixed B- and T-cell infiltrates, and encapsulated budding yeasts (5-10 μm) within enlarged perivascular spaces. Gomori Methenamine Silver and periodic acid-Schiff staining confirmed fungal elements; culture identified Conclusion: Skull cryptococcosis in immunocompetent patients is rare but can occasionally present as an inflammatory pseudotumor with osteomyelitis and extracranial extension. Its imaging resemblance to aggressive neoplasms underscores the importance of including fungal etiologies in the differential diagnosis of destructive skull lesions, regardless of the immune status.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.