Evidence map›Paper›PMID 41660349›Full record

ReviewSurgical neurology international2026

Thalamic gliomas: A systematic review and meta-analysis.

Ali K Al-Shalchy, Rania H Al-Taie, Nooruldeen H Ali Al-Khafaji, Mohammed A Bani Saad, Younus M Al-Khazaali, Ali Akram Shahadha, Mostafa H Algabri, Mohammed Adnan Hazim, Mustafa Ismail

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Review in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ali K Al-ShalchyDepartment of Surgery, College of Medicine, University of Baghdad, Baghdad, United States.
Rania H Al-TaieDepartment of Surgery, College of Medicine, Mustansiriyah University, Baghdad, United States.
Nooruldeen H Ali Al-KhafajiDepartment of Surgery, College of Medicine, University of Baghdad, Baghdad, United States.
Mohammed A Bani SaadDepartment of Surgery, Al-Kindy Teaching Hospital, Baghdad, United States.
Younus M Al-KhazaaliDepartment of Surgery, College of Medicine, Al-Nahrain University, Baghdad, United States.
Ali Akram ShahadhaDepartment of Neurosurgery, Dr. Saad ALWitry Hospital for Neurosciences, Baghdad, United States.
Mostafa H AlgabriDepartment of Surgery, Baghdad Teaching Hospital, Baghdad, United States.
Mohammed Adnan HazimDepartment of Surgery, College of Medicine, University of Baghdad, Baghdad, United States.
Mustafa IsmailDepartment of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Thalamic gliomas are rare tumors with unique anatomical and histopathological characteristics which make them challenging to identify and manage. The aim of the present meta-analysis is to consolidate the evidence for clinical outcomes, tumor grade, laterality, operation type, and complications of thalamic gliomas. Methods: We conducted a Preferred Reporting Items for Systematic Reviews and Meta-analyses - conformant systematic review and meta-analysis. 327 patients were included in 15 studies. Statistical analysis included heterogeneity testing for tumor grades, laterality, and outcome of operations using pooled proportions. Dichotomous outcomes were analyzed using odds ratios (ORs) and random-effects models. Complications and adjuvant treatments were also examined. Results: The statistical analysis showed a significant association between tumor grade and clinical outcome, with clinical improvement occurring in 83% of low-grade versus 46% of high-grade thalamic gliomas (odds ratio = 0.366; Conclusion: Tumor grade remains the strongest prognostic factor in thalamic glioma surgery. While laterality and extent of resection appear less predictive, tailored surgical approaches supported by advanced imaging and intraoperative monitoring can optimize outcomes. Further research incorporating molecular subtypes is warranted to refine surgical strategies and prognosis.

Indexed as

Surgical approachesThalamic gliomaTreatment outcomesTumor gradingTumor laterality

Identifiers

PMID41660349
PMCPMC12875233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.