ArticleiScience2026
Multimorbidity and mortality trends in the COVID19 syndemic in Madagascar covering 180 diseases 2015 2024.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multimorbidity and mortality shape population health in Madagascar, where chronic and infectious diseases interact across regions. Using surveillance data covering 180 diseases across 22 regions from 2015 to 2024, we quantified geographic disparities, dominant contributors to disease burden, and shifts associated with the COVID-19 syndemic. Stroke was the leading cause of death, with regional case-fatality rates often exceeding 45% and reaching nearly 99% for cardiac arrest in some urban areas. Stroke also showed strong correlations with hypertension (r = 0.97) and diarrhea (r = 0.98), highlighting interconnected vulnerabilities. During the COVID-19 period, overall disease frequency increased by 6.12% on average, though responses varied widely across conditions. Post-lockdown, incidence declined substantially (MRD = -90.17%), and mortality decreased slightly (MRD = -3.93%), yet disparities persisted. Groups with cardiovascular and mental health disorders exhibited the greatest instability. These findings illustrate how interacting epidemics reshape population vulnerability and underscore the importance of integrated strategies to strengthen health-system resilience.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.