Evidence map›Paper›PMID 41660253›Full record

ArticleiScience2026

BCG immunotherapy for bladder cancer triggers systemic and local BCG-specific CD4

Paul Rollin, Benjamin Pluskwa, Emilie Artru, Tristan Le Vaslot, Daria Kartasheva-Ebertz, Diane Biron, Margaux Bossis, Fanny Onodi, Joel LeMaoult, Nathalie Rouas-Freiss and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Paul RollinInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Benjamin PluskwaInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Emilie ArtruInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Tristan Le VaslotInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Daria Kartasheva-EbertzInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Diane BironInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Margaux BossisInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Fanny OnodiInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Joel LeMaoultInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Nathalie Rouas-FreissInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Mathieu F ChevalierInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Cecilia S Lindestam ArlehamnCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, San Diego, CA, USA.
Alessandro SetteCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, San Diego, CA, USA.
Alexandra Masson-LecomteInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
François DesgrandchampsInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Evanguelos XylinasInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.
Pierre TonnerreInstitut de Recherche Saint-Louis, Université Paris-Cité, Inserm U1342, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-risk non-muscle-invasive bladder cancer (NMIBC) is treated with intravesical instillations of Bacillus Calmette-Guérin (BCG), which trigger a local immune response. Improved patient outcomes have been linked to the recruitment of CD4

Indexed as

immune responseimmunologyoncologytherapeutics

Identifiers

PMID41660253
PMCPMC12877854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.